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| Paper Type | : | Research Paper |
| Title | : | Status study of medicinal plants at Purnapani forest of Jhargram in West Bengal |
| Country | : | India |
| Authors | : | Naina Goswami || Debabrata Das |
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: | 10.9790/3008-1304060112  |
Abstract: Sal based vegetation of Purnapani is under Binpur-I community Development Block in the newly formed district Jhargram of West Bengal. It is important because it is an associated corridor of Jhitka-Lalgarh forest under Jhargram Forest Division (Formerly Medinipur Forest Division) which is open corridor for Dalma Elephant (including residential kind). It was famous because of recorded 'The Royal Bengal Tiger', reported first time. Now it is a forest filled with coppice sal (Shorea robusta) along with many valuable medicinal plants, timber yielding crops, mushrooms. The forest includes a variety of birds, butterflies including insects round the year. The forest comprised of a large number............
Keywords: Purnapani, Coppice sal forest, medicinal plants, ecological status, conservation
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| Paper Type | : | Research Paper |
| Title | : | Comparability in bioactivity assays of 45s5 bioglass scaffolds using simulated body fluid and rabbit blood plasma |
| Country | : | México |
| Authors | : | Abad-Javier, M.E. || Nuñez-Anita, R.E. || Cajero-Juárez, M. || Contreras-García, M.E |
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: | 10.9790/3008-1304061323 |
Abstract: Currently the development of viable biomaterials for replacement of damaged or lost tissue has become a humanitarian need due to the large number of degenerative syndromes and traumas, compromising the tissue and surrounding organs. 45s5 bioactive glass has been exhaustively studied around the world forbonereplace, but it does exist several factors involved in the bioactivity which need to be analyzed, such as local protein presence or differences in carbonate disposition in the surrounding medium. Bioactive scaffolds made of bioglass 45s5 were prepared by the sol-gel via coupled to spray drying, employing polystyrene microspheres as template agents and heat treatment at 700 °C. The bioactivity was examined in vitro with simulated body fluid (SBF) and rabbit blood............
Keywords –Bioglass, SBF, rabbit-blood-plasma, bioactivity, hydroxyapatite-morphology
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[2] M. Bohner and J.Lemaitre, Can bioactivity be tested in vitro with SBF solution?, Biomaterials, 30, 2009, 2175–2179.
[3] C. Vichery and J.M. Nedelec, Bioactive Glass Nanoparticles: From Synthesis to Materials Design for Biomedical Applications, Materials, 9(4), 2016, 288-304.
[4] L.C. Gerhardt and A. R. Boccaccini, Bioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering, Materials (Basel), 3(7), 2010, 3867–3910.
[5] A. Oyane, H.M. Kim, T. Furuya, T. Kokubo, T. Miyazaki, and T. Nakamura, Preparation and assessment of revised simulated body fluids, J Biomed Mater Res, 65, 2003, 188–195
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| Paper Type | : | Research Paper |
| Title | : | Ethnobotanical Survey Of Medicinal Plants Used For Treatment Of Malaria By Kipsigis People In Kericho County, Kenya. |
| Country | : | Kenya |
| Authors | : | Bwogo ChepchumbaPacifica || Dr. Benson Nyanchongi || Dr. Rael Masai |
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: | 10.9790/3008-1304062430 |
Abstract: Background: Ethnobotanical pharmacopoeia is importantly used in intervention of disease and need arises for documentation and preservation of tradition medicinal knowledge to boost the discovery of new drugs. Due to the emergence of drug resistance to malaria, there is a high possibility of development of resistance to ACT (that is the first line of treatment), thus a need for identification and development of new and novel therapeutic approaches. Herbs offer an opportunity for discovery and development of new chemically diverse antimalarial agents, however little documentation has been done. The first objective of the present study was to identify and document preferred medicinal plants used for treatment of malaria in Kericho East Sub-County.........
Keywords: Medicinal plants, Traditional medicine, Kericho, Ethnobotanicalsurveys, Conservation
[1]. Kokwaro, J.O., 1993. Medicinal Plants of East Africa, 2nd ed. Kenya Literature Bureau of Kenya, Nairobi.
[2]. Koshy, P., Sri Nurestri, A., Wirakarnain, M. S., Saravan, K., Hong, S. L., Lee, G. S. and Syrarifah, N.S., 2009. Antimicrobial Activity of Some Medicinal Plants of Malaysia. Malaysia. America Journal of AppliedSciences 6 (8): 1613–1617.
[3]. Bussmann, R. W. (2006). Ethnobotany of the Samburu of Mt. Nyiru, SouthTurkana, Kenya, 10, 1–10. http://doi.org/10.1186/1746-4269-2-35
[4]. Gachati, F.N., 1989. Kikuyu Botanical Dictionary of plant names and uses.
[5]. WHO, 2003. Traditional Medicine..
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| Paper Type | : | Research Paper |
| Title | : | Human Chorionic Gonadotropin Level in Iraqi Women with Pregnancy-Induced Hypertension |
| Country | : | Iraq |
| Authors | : | Saja Muhanad Bayram || Lina A. Salih || Samia. A. Eleiwe |
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: | 10.9790/3008-1304063135 |
Abstract: Pregnancy-induced hypertension (PIH)is a major pregnancy complication that lead to maternal mortality.Here, we have scrutinized the correlation between serum level of biochemical parameters and oxidative stress parameter in PIH.Serum samples were collectedfromeighty Iraqi women (forty women with pregnancy-induced hypertension as patients group, twenty normotensive pregnant women as a positive control, and twenty normotensive non-pregnant women as a negative control) all groups were diagnosed clinically. A questionnaire form included for all studied groups and contain Age and gestational age. Serum -hCG hormone levelwas determined for all studied groups. Age range was between (17-50) years and there were no significant (P<0.01) differences in means...........
Keywords: PIH, β-hCG, Iraq, Baghdad
[1]. Haram, K., J.H. Mortensen, and B. Nagy, Genetic aspects of preeclampsia and the HELLP syndrome.Journal of pregnancy. 2014.
[2]. Beharier, O., et al., Preeclampsia and future risk for maternal ophthalmic complications.American journal of perinatology. 33(07), 2016, 703-707.
[3]. Damani, Z., Platelet count in women with pregnancy induced hypertension in university hospital center of mother and child healthcare "koco gliozheni", Tirana, Albania.Materia socio-medica. 28(4), 2016, 268.
[4]. Paulesu, L., et al., hCG and its disruption by environmental contaminants during human pregnancy.International journal of molecular sciences. 19(3), 2018, 914.
[5]. Androutsopoulos, G., P. Gkogkos, and G. Decavalas, Mid-trimester maternal serum HCG and alpha fetal protein levels: clinical significance and prediction of adverse pregnancy outcome.International journal of endocrinology and metabolism. 11(2), 2013, 102.
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| Paper Type | : | Research Paper |
| Title | : | Antimicrobial Activity of Leaf Extract of Anogeissus Leiocarpus (African Birch) On Some Selected Clinical Isolates. |
| Country | : | |
| Authors | : | Dayok O || Dawang , D.N || Da'am, C. E |
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: | 10.9790/3008-1304063640 |
Abstract: The comparative study on the antimicrobial activity of ethanolic and aqueous extracts of Anogeissus leiocarpus (African birch) leaf against Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus mutans was evaluated in this research. The phytochemical analysis of both ethanolic and aqueous leaf extracts of Anogeissus leiocarphus (African birch) revealed the presence of saponine, tannins, steroide, cardiac glycoside, flavonoide and anthraquinone. There was antimicrobial activity for ethanolic extract against the test organisms with higher zones of inhibition on Pseudomonas aeruginosa ranging from 14mm-18mm than Staphylococcus aureus which ranged from 11mm-17mm, followed by Streptococcus mutans which ranged from 10mm-15mm. However, the aqueous extract revealed.............
Keywords: Anorgeissus leiocarpus extract, efficacy, test bacteria
[1]. Arbonnier, M. (2004). Trees, shrubs and lianas of West African Dry zones. Life science Journal (11), 172-99.
[2]. Bukar,B.B, Dayom W.D and Uguru,O.M (2016).The Growing Economic Importance of Medicinal Plants and The Need For Developing Countries To Harness From it: A Mini Review. IOSR Journal Of Pharmacy, 6(5), 42-52.
[3]. Habamu, Y, T. Eguale, A, Wubete,A & Sori, T,(2010). Invitro antimicrobial activity of selected Ethiopian medicinal plants against some bacteria of Veterinary importance. African Journal microbial Research. 4:1230-1234.
[4]. Li J , Xie S, Ahmed S, Wang F , Gu Y, Zhang C, Chai X , Wu Y, Cai J, and Cheng G (2017). Antimicrobial Activity and Resistance: Influencing Factors. Front Pharmacol., 8: 364.
[5]. Mann, A, Gbate, M. Umar, N.A, (2003). Medicinal and economic plants from Nupe land. Jube. Evans publisher p. 67...
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| Paper Type | : | Research Paper |
| Title | : | Study The Toxic Effect Of Different Doses Of Duprost On Spleen Of Albino Mice |
| Country | : | Iraq |
| Authors | : | Ban Jasim Mohamad || Hind Hussein Obaid || ReyadhSalim Mohammed || FaizaAftan Zghair || Rasmiya Abd Aboresha || Zainab Zamel Khalaf |
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: | 10.9790/3008-1304064145 |
Abstract: The intent of this task was to examine the toxic effect of different dosages of Duprost (dutasteride) on
the spleen of mice.
Methods: Twenty four albino mice were purchased and fractioned into three parts: control (3 mice), acute group (12 mice) and chronic group (9 mice). The acute group was subdivided to 4 groups, each of which contained 3mice. Every group was given a lonely oral dose of the following doses: subgroup1 dosed with 0.25ml (0.5 mg\kg of Duprost, subgroup2 0.15ml (0.12mg\kg) dose, subgroup3 0.1 ml (0.08mg\kg) dose and subgroup4 0.05ml (0.04mg\kg) dose of Duprost for 24 hours. Whereas the chronic group was subdivided into 3 subgroups and each set was given a daily dose of (0.15ml, 0.1ml, and 0.05 ml of Duprost respectively) for 42 days. After
the mentioned periods, the mice of all groups were sacrificed and the spleen of each animal was removed, processed, sectioned and stained for histological analysis........
[1]. Wein AJ, et al., 2017. Benign prostatic hyperplasia: Etiology, pathophysiology, epidemiology, and natural history. In: Campbell-Walsh Urology. 11th ed. Philadelphia, Pa.: Elsevier. https://www.clinicalkey.com.
[2]. National Institute of Diabetes and Digestive and Kidney Diseases.2017. https://www.niddk.nih.gov/health-information/urologic-diseases/prostate-problems/prostate-enlargement-benign-prostatic-hyperplasia.
[3]. American Urological Association. http://www.auanet.org/guidelines/benign-prostatic-hyperplasia-(2010-reviewed-and-validity-confirmed-2014). Accessed Sept. 25, 2017.
[4]. Cunningham GR, et al. 2017. Clinical manifestations and diagnostic evaluation of benign prostatic hyperplasia. https://www.uptodate.com/contents/search.
[5]. Ferri FF. 2018. Benign prostatic hyperplasia. In: Ferri's Clinical Advisor, Philadelphia, Pa.: Elsevier; https://www.clinicalkey.com
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| Paper Type | : | Research Paper |
| Title | : | Effects of the Aqueous and Methanol Extracts of Alchornea Laxiflora in Rodent Models of Experimental Psychosis |
| Country | : | Nigeria |
| Authors | : | C.N.S. Nwonu || O.R. Ilesanmi || J.M. Agbedahunsi || P.C. Nwonu |
|
: | 10.9790/3008-1304064652 |
Abstract: The study investigated the median lethal dose and the effects of the aqueous and methanol extracts of Alchornea laxiflora in two mouse models of experimental psychosis, the apomorphine-induced climbing behavior and apomorphine-induced stereotypy tests. This was with a view to providing information on the acute toxicity and the antipsychotic potential of the plant extracts. Mice of both sexes (n=6) weighing 18 – 22 g were used for the study, which were randomized into control and test groups, which summed up to seven (7) groups. The control group (1) received 10 % Tween 80 (vehicle), 0.1 ml/10 g mouse while the test groups (II, III, IV, V, VI) were administered graded doses (100, 200, 400, 800, 1600 mg/kg, p.o.) of the extracts. The standard group (VII) received a standard drug, Chlorpromazine (2 mg/kg, i.p.). The animals were observed for climbing and stereotypic behaviours in a wire mesh........
Keywords: Alchornea laxiflora, antipsychotic, climbing, chlorpromazine, mice and stereotypy
[1]. Hutchinson, J. and Dalziel, J.M. (1937): Flora of West Tropical Africa. Crown Agents for Overseas Government and Administration, London, Vol. 1 (2): 600 – 605.
[2]. Adewole, A.A. (1993): Personal communication with local traditional medical practitioners in Ibadan, Nigeria.
[3]. Muanya, C. (2009): Herbal medication shows promise in the management of Sickle cell anaemia. The Guardian, February 19, Pp. 35 – 36.
[4]. Farnsworth, N.R., Akerele, O., Bingel, A.S., Soejarto, D.D. and Guo, Z.G. (1985): Medicinal plants in therapy, Bull. WHO 63: 965 – 981.
[5]. Burkill, H.M. (1994):6The useful plants of West Tropical Africa, Edition 2, Vol. 2, Families E-I (Royal Botanic Gardens, Kew, Pp. 144 − 150.
[6]. Ogundipe, O.O., Moody, J.O., Houghton, P.J. and Odelola, H.A. (2001): Bioactive chemical constituents from Alchornea laxiflora (Benth.) Pax and Hoffman. Journal of Ethnopharmacology 74 (3): 275 − 280.
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| Paper Type | : | Research Paper |
| Title | : | Screening of Analgesic Activity of Methanolic Extract and Its Fractions of Alternanthera Pungens |
| Country | : | India |
| Authors | : | G. Kalpana || K. Sruthi || Zeenath Banu || M. Sumakanth || A.Ravindernath || D. Jaya Prakash |
|
: | 10.9790/3008-1304065358 |
Abstract: The purpose of the present study was to prepare the methanolic extract and various fractions of whole plant of Alternanthera pungens and to perform preliminary phytochemical analysis and screening of analgesic activity using Tail Immersion method on Swiss albino mice. The whole plant of Alternanthera pungens was collected, powdered and extracted with methanol by maceration method. The obtained methanolic extract was fractioned into various fractions (P2 and C2) using different solvents of increasing order of polarity viz., Petroleum ether and chloroform successively and the residue left over is Hydro alcoholic fraction (H2). Preliminary phytochemical analysis of the obtained extract and fractions revealed the presence of steroids, triterpenoids, phenols and flavonoids rich in methanolic and chloroform fractions (M2 and C2). The extract and its fractions were significantly (p<0.001) reduced the pain as compare to the control group. Among all extract and fractions chloroform fraction (C2) was found to possess good analgesic activity.
[1]. Kulkarni S K (2007), Handbook of experimental pharmacology, Vallabh prakashan, New Delhi.
[2]. Parle Mand Yadav M, Laboratory Models For Screening Analgesics, International Research Journal Of Pharmacy, 2013;4 (1):15-19
[3]. Ayurvedic Pharmacopoeia(1996), Ministry of Health and Family Welfare, Govt. of India (ed 1), New Delhi.
[4]. https://uses.plantnet-project.org/en/Alternanthera_pungens_(PROSEA).
[5]. HundiwaleJogendra C, PatilAvinash V, Kulkarni Mohan V, Patil D.A. and Mali Ravindra GA current update on
phytopharmacology of the genus Alternanthera. Journal of Pharmacy Research. 2012;5(4):1924-1929.
[6]. Petrus, A. J. A.; Seetharaman, T. R. Antioxidant flavone C-biosides from the aerial parts of Alternanthera pungens. Indian Journal
of Pharmaceutical Sciences, 2005; 67(2):187-193.
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| Paper Type | : | Research Paper |
| Title | : | Characterization and Antimicrobial Activity of AgNPs Synthesized by Streptomyces sp. RHS16 Against Fish Pathogens |
| Country | : | Egypt |
| Authors | : | Rana F. El Baradaei || Samia S. Abouelkheir || Hanan A. Ghozlan || Soraya A. Sabry |
|
: | 10.9790/3008-1304065967 |
Abstract: Silver nanoparticles (AgNPs) attracted great attention due to their unusual and fascinating properties, and applications in many fields.This work reports thefabrication of AgNPsby a newly isolated Streptomycessp. RHS16. The synthesis of silver nanoparticles was mediated by nitrate reductase enzyme secreted in the culture filtrate of the bacterium and detected using UV-visible spectra that showed a strong and broad peak between 420nm and 450nm. The effect of crude enzyme concentration and silver nitrate molarity was evaluated. As the volume of crude enzyme increased from 1ml to 4ml, the color changed to dark reddish brown and the absorbance values............
Keywords:Silver nanoparticles,Streptomyces sp. RHS16, Biosynthesis, Antimicrobial activity, Fish pathogens,XRD, TEM, SEM, EDX, and FTIR
[1]. Abou El-Nour, K.M., Eftaiha, A., Al-Warthan, A.&Ammar, R.A. (2010).Synthesis and applications of silver nanoparticle.Arabian Journal of Chemistry. 3: 135–140.
[2]. Arunachalam, K.D., Annamalai,S.K., Hari, S. (2013). One-step green synthesis and characterization of leaf extract-mediated biocompatible silver and gold nanoparticles from Memecylonumbellatum. International Journal of Nanomedicine. 8(1): 1307—1315.
[3]. Balakumaran, M.D., Ramachandran, R., Balashanmugam, P., Mukeshkumar, D.J. Kalaichelvan,P.T. (2016).Mycosynthesis of silver and gold nanoparticles: Optimization, characterization and antimicrobial activity against human pathogens. Microbiological Research. 182: 8-20.
[4]. Ben-David, A., & Davidson, C.E. (2014).Estimation method for serial dilution experiments.Journal of Microbiological Methods. 107: 214-221.
[5]. Borase, H.P., Salunke, B.K., Salunkhe, R.B., Patil, C.D., Hallsworth, J.E., Kim, B.S., Patil, S.V. (2014). Plant extract: a promising biomatrix for ecofriendly, controlled synthesis of silver nanoparticles. Appl Biochem Biotechnol. 173(1):1-29.
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| Paper Type | : | Research Paper |
| Title | : | Assessment of Serum Galectin-8 in Iraqi Patients with Rheumatoid arthritis |
| Country | : | Iraq |
| Authors | : | Tarek.Q.Muss || M.AL-Faham || Faiq I.Gorial |
|
: | 10.9790/3008-1304066871 |
Abstract:Background:Rheumatoid arthritis (RA) is chronic inflammatory arthritis disease with significant morbidity and mortality .Early diagnosis is important for better treatment and outcome.Galectins are potent immune regulators and modulate a range of pathological processes, such as inflammation, autoimmunity, and cancer, Accumulated evidence shows that several family members of galectins play positive or negative roles in the disease development of RA, through their effects on T and B lymphocytes, myeloid lineage cells, and fibroblast-like synoviocytes. (1).
Objective: to assessserumGalectin-8 in Iraqi Patients with RA and its validity in diagnosis of RA Patients and Methods: This case control study included 90 subjects.Fiftyof them were patient diagnosed as established RA according to........
Keywords- Rheumatoid arthritis,Galectin-8,inflammatory arthritis
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[3]. Brennan FM, Hayes AL, Ciesielski CJ, Green P, Foxwell BM, Feldmann M: Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: involvement of phosphatidylinositol 3-kinase and nuclear factor kappaB pathways in tumor necrosis factor alpha production in rheumatoid arthritis. Arthritis Rheum 2002, 46:31-41.
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| Paper Type | : | Research Paper |
| Title | : | Phytochemical And Pharmacological Screening Of Ethanolic Extract Of Clerodendrumphlomidis |
| Country | : | India |
| Authors | : | Ashok Subedi || Mohammed Vazir |
|
: | 10.9790/3008-1304067274 |
Abstract: Cancer is one of the most life-threatening diseases in which deregulating proliferation of abnormal cells invades and disrupts surrounding tissues. It constitutes serious public health problems in both developed and developing countries. About 12.7million people were diagnosed with cancer across the world in 2008, and 7.6million people died from the cancer during the same year. Lung cancer, breast cancer, colorectal cancer and stomach cancer accounted for two-fifths of the total cases of cancers diagnosed worldwide. More than 70% of all cancer deaths occurred in low-and middle-income countries, Deaths due to cancer are projected to continuously increase and it has been estimated that there will be 11.5million deaths in the year 2030 and 27million new cancer cases and 17.5million cancer deaths are projected to occur in the world by 2050. Natural compounds have been.........
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[3]. Vijay R.C ,Krishnakant N.P, Havagiray R.C and Shruti S. Pre clinical evolutionary study of Clerodendrum phlomidis as a nanti-obesity agent against high fat diet induced C57BL/6Jmice. Asian Pacific Journal of Tropical Biomedicine2012:S1509-S1519.
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[5]. Bhatnagar S and Pattanaik S. Comparative analysis of cytotoxic and antioxidant activities of leaf and bark extracts of Clerodendrum viscoum and Clerodendrum phlomidis. International Journal of Biomedical and Advance Research.2012;03(05):385-90