Abstract: This study was aimed at investigating the Antifungal susceptibility profile of Genitourinary Candida species among women attending a tertiary hospital in Abakaliki, Nigeria. One hundred and five swab specimens were collected. Fifty one were endocervical swab specimens (ECS) while Fifty four were vaginal swab specimens (VS). The specimens were analysed using standard microbiological methods. Wet preparations were examined for the presence of yeast cells. Antibiogram of Candida isolates obtained from this study was carried out using commercially available azole drugs. Fluconazole, voriconazole and nystatin were the drugs used for this study. The Kirby Bauer disc diffusion method was employed. Out of 105 specimens collected, 68.6% (n=72) were positive for the presence of Candida. Non Candida albicans Candida was predominant (65.3%) as against C. albicans (34.7%). Fluconazole was sensitive in 34.7% of the isolates and resistant in 65.3%. Voriconazole was sensitive in 81.9% of the isolates and resistant in 18.9%. Nystatin was sensitive in 23.6% of the isolates and resistant in 76.4%. Generally the highest rate of sensitivity was recorded with Voriconazole and the highest rate of resistance was recorded with Nystatin. Prompt diagnosis and employment of very standard techniques in assessing the antifungal susceptibility profile of Candida species is highly recommended.
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