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| Paper Type | : | Research Paper |
| Title | : | Anti-Obesity Potential of Heritiera Fomes Leaves Methanolic Extract in a Preclinical Model |
| Country | : | India |
| Authors | : | M.Salim Mirza || Sayed Ayaz Ali || Indrajeet Sanghvi |
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: | 10.9790/3008-1204010105  |
Abstract: Objective: This study was undertaken to evaluate the anti-obesity potential of the methanolic extract of leaves of Heritiera fomes. (MEHF) in high fat cafeteria diet (HFCD) fed obese rats.
Methods: Wistar strain of albino rats were divided into six groups comprising of six rats each. Group I served as normal control fed with normal pellet chow, group II served as disease control fed with high fat cafeteria diet, group III, IV and V animals, received MEHF at a dose level of 100, 200 and 400mg/kg b.w along with HFCD for 40 days, while, group VI served as standard drug control, which received Orlistat at a dosage of 50mg/kg b.w along with HFCD.............
Keywords: High Fat Cafeteria diet, Obesity, Heritiera fomes, Orlistat.
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[4]. Ali, K. Nahar, M. Sintaha et al., "An evaluation of antihyperglycemic and antinociceptive effectsof methanol extract of Heritiera fomes Buch- Ham. (Sterculiaceae) barks in Swiss albino mice," Advances in Natural and Applied Sciences, vol. 5, no. 2, pp. 116–121, 2011.
[5]. M. A. Hossain, S. Panthi, M. Asadujjaman, S. R. Khan, F. Ferdous, and S. K. Sadhu, "Phytochemical and pharmacological assessment of the ethanol leaves extract of Heritiera fomes Buch. Ham. (Family- Sterculiaceae)," Journal of Porphyrins and Phthalocyanines, vol. 2, pp. 95–101, 2013.
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| Paper Type | : | Research Paper |
| Title | : | Evolution of Reovirus in Cancer Therapy |
| Country | : | India |
| Authors | : | Bindhu Jayaprakash || Sivapriya Veeraiyan || Silambarasan Gunaseelan || Yasodha Purushothaman |
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: | 10.9790/3008-1204010614 |
Abstract: The overactive Ras signaling can ultimately lead to cancer. The 3 Ras genes in humans (HRas, KRas, and NRas) are the most common oncogenes in human cancer.Mutations that permanently activate Ras are found in 20% to 25% of all human tumors and up to 90% in certain types of cancer (e.g., pancreatic cancer). For this reason, Ras inhibitors are being studied as a treatment for cancer and other diseases with Ras overexpression. Reovirus was noted to be a potential cancer therapeutic when studies suggested it reproduces well in certain cancer cell lines..............
Keywords: Reovirus, monotherapy, anticancer
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[3] 24 Lal R, Harris D, Postel-Vinay S, de Bono J (October 2009). "Reovirus: Rationale and clinical trial update". Curr. Opin. Mol. Ther. 11 (5): 532–9. PMID 19806501.
[4] Coffey MC, Strong JE, Forsyth PA, Lee PW. Reovirus therapy of tumors with activated Ras pathway. Science. 1998;282(5392):1332–1334. [PubMed]
[5] Schirrmacher V, Fournier P. Newcastle disease virus: a promising vector for viral therapy, immune therapy, and gene therapy of cancer. Methods Mol Biol. 2009;542:565–605. [PubMed].
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| Paper Type | : | Research Paper |
| Title | : | Male Aphrodisic Screening of Plants Mucuna Prurita, Mesua Ferrea, Punica Granatum on Rats |
| Country | : | India |
| Authors | : | Sonu Sharma || Dr. Ashish K. Sharma |
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: | 10.9790/3008-1204011527 |
Abstract: India has a rich culture of medicinal herbs and spices, including Ayurvedic, Unani, Siddha and other traditional medicines but only very few have been studied chemically and pharmacologically for their potential medicinal value. According to the World Health Organization, most populations still rely on traditional medicines for their psychological and physical health requirements. Herbal medicines are in great demand in both developed and developing countries as a source of primary health care owing to their attributes having wide biological.............
Keywords: Pruritus, Haemorrids, Ulcers, Depsia, Impotency, Leucorrhoea, Haemoptysis, Cephalalgia, Fever , Cardiac Debility.
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[3] Singh Shiv Pal. Fertility Control of Female through SesbaniSesbian Seeds. The Journal of Research and Education in Indian Medicine. 1990; 9 (4): 27- 32.
[4] ShahuAlakh N. Phyto-pharmacological review of mesuaferrealinn. International Journal OfPhytopharmacology. 2014; 5(1): 6-14.
[5] Ramya R, Sivasakthi R, Senthilkumar C, Anudeepa J, Santhi N, Venkata Narayanan N: Preliminary phyto chemical and anti fertility Studies on Dodonea viscose Linn.Asian Journal Res Pharm Sci, 2011; 1 : 77-79
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| Paper Type | : | Research Paper |
| Title | : | Prevalence of Antibiotic Resistance in Clinical Strains of E. Coli and Their Control |
| Country | : | India |
| Authors | : | Sujatha.J || Anusuya.P |
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: | 10.9790/3008-1204012833 |
Abstract: The present study was to evaluate the isolates of antibiotic resistant E. coli in clinical samples and their control. A total of 50 E. coli strains were isolated from samples such as ENT, Pus and UTI. 5 different antibiotics were tested. 20% of the strains showed resistance to single antibiotic (AMP, AMX), whereas rest of the strains to 2-5 antibiotics (i.e.) AMP-AMX (6%); AMP-AMX-CXM (16%), AMP-AMX-CN (20%), AMP-AMX-CN-CPD (20%), and AMP-AMX-CXM-CN-CPN (18%). MAR index for the isolates was found to be from 0.4-1.0..............
Keywords: E.coli, Haemolytic, β-lactam, Antibiotic resistance
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