iosr-JDMS   Volume-22 ~ Issue-9 ~ Sep. 2023

Abstract: Background: Stroke is a cerebrovascular accident (CVA), which is a significant reason for morbidity and mortality. Melatonin is produced by the pineal gland to regulate circadian rhythm including light-dark cycles among mammals. It is present in cerebrospinal fluid, bile, ovarian follicular fluid, and the anterior chamber of the eye, suggesting its main role apart from regulating the internal clock. In view of the high prevalence of stroke, and less literature on its effective management, the current study was undertaken........

Key Word: Stroke, Melatonin, Cerebrovascular accident, Embolism, Efficacy, Safety

[1] Adams HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE. Classification Of Subtype Of Acute Ischemic Stroke. Definitions For Use In A Multicenter Clinical Trial. TOAST. Trial Of Org 10172 In Acute Stroke Treatment. Stroke. 1993 Jan;24(1):35-41. [Pubmed]
[2] Ntaios G. Embolic Stroke Of Undetermined Source: JACC Review Topic Of The Week. J Am Coll Cardiol. 2020 Jan 28;75(3):333-340. [Pubmed]
[3] Pierik R, Algra A, Van Dijk E, Erasmus M Et Al. On Behalf Of The Parelsnoer Institute-Cerebrovascular Accident Study Group. Distribution Of Cardioembolic Stroke: A Cohort Study. Cerebrovasc Dis. 2020;49(1):97-104. [Pubmed]
[4] The Top 10 Causes Of Death [Internet]. Who.Int. [Cited 2023 Aug 07]. Available From: Https://Www.Who.Int/En/News-Room/Fact-Sheets/Detail/The-Top-10-Causes-Of-Death
[5]. Tan D., Manchester L.C., Reiter R.J., Qi W., Hanes M.A., Farley N.J. High Physiological Levels Of Melatonin In The Bile Of Mammals. Life Sci. 1999; 65:2523–2529. Doi: 10.1016/S0024-3205(99)00519-6. [Pubmed] [Crossref] [Google Scholar.

Abstract: Radicular cysts are the most common odontogenic cyst found in oral cavity accounting for more than 50% of the total odontogenic cysts. They usually remain asymptomatic unless and until it becomes larger in size. In some cases, small radicular cysts get diagnosed during routine radiographs and such small lesions can be managed conservatively by endodontic treatment whereas large radicular cysts needs surgical intervention post root canal treatment. In this article we have reported two such cases of giant radicular cysts (one in maxilla and mandible each) which were treated effectively by means of root canal treatment followed by surgical enucleation and showed significant healing postoperatively.

Key Word: Word: Radicular cyst, Enucleation, Apicoectomy, Cell rest of Malassez.

[1]. Naveed N. Radicular Cysts And Treatment Concepts.
[2]. Kolari V, Rao Ha, Thomas T. Maxillary And Mandibular Unusually Large Radicular Cyst: A Rare Case Report. National Journal Of Maxillofacial Surgery. 2019 Jul;10(2):270.
[3]. Agarwal P, Sharma S, Trehan M, Vashistha A. Management Of Infected Radicular Cyst By Marsupialization. World J Dent. 2013 Jul;4(3):214-6.
[4]. Latoo S, Shah Aa, Jan Sm, Qadir S, Ahmed I, Purra Ar, Malik Ah. Radicular Cyst. Jk Science. 2009 Oct 1;11(4):187.
[5]. Velasco I, Vahdani S, Nuñez N, Ramos H. Large Recurrent Radicular Cyst In Maxillary Sinus: A Case Report. Int. J. Odontostomat [Internet]. 2017 Apr;11(1):101-5

Abstract: This case report demonstrates the MRI orbit findings in a young female who presented with diminution of vision with fundus findings of morning glory disc. On MRI, funnel shaped morphologic pattern resembling characteristic 'morning glory' was revealed for bilateral optic discs. Embryology and genetics of this rare entity are also discussed briefly. Finally, conclusion was made that of bilateral ocular colobomas with characteristic MRI imaging features.

Keywords: Ocular coloboma, morning glory, scotoma, optic fissure, MRI orbit

[1]. Tawfik, H. A., Abdulhafez, M. H., Fouad, Y. A., & Dutton, J. J. (2016). Embryologic And Fetal Development Of The Human Eyelid. Ophthalmic Plastic &Amp; Reconstructive Surgery, 32(6), 407–414.
[2]. Lingam, G., Sen, A. C., Lingam, V., Bhende, M., Padhi, T. R., & Xinyi, S. (2021). Ocular Coloboma—A Comprehensive Review For The Clinician. Eye, 35(8), 2086–2109.
[3]. Nakamura, K. M. (2011). Incidence, Ocular Findings, And Systemic Associations Of Ocular Coloboma. Archives Of Ophthalmology, 129(1), 69.
[4]. Murphy, B. L., & Griffin, J. F. (1994). Optic Nerve Coloboma (Morning Glory Syndrome): CT Findings. Radiology, 191(1), 59–61.
[5]. Schubert, H. D. (2006). Structural Organization Of Choroidal Colobomas Of Young And Adult Patients And Mechanism Of Retinal Detachment. American Journal Of Ophthalmology, 142(2), 367.

Abstract: Dental implant is the best treatment option for a lost tooth in today's era of modern dentistry. Placing implant in esthetic zone, it is imperative to understand bone quality and bone volume as well as give equal importance to the esthetic expectations of the patient. Alveolar ridge defects occur due to maxillofacial trauma, accidents, traumatic tooth extraction, and advanced periodontal diseases. Defects that occur in bone and soft tissue can be horizontal or vertical in nature. This defect can be corrected by various reconstruction techniques like soft tissue or bone graft, guided bone regeneration. This case demonstrates the replacement of missing maxillary anterior tooth using screw-retained implant prosthesis after guided bone regeneration.

Key word: mucoperiosteal facial flap, DFDBA, bone graft, temporary restoration, labial ridge deformity

[1]. F. G. Mangano, P. Mastrangelo, F. Luongo, A. Blay, S. Tunchel, and C. Mangano, "Aesthetic outcome of immediately restored single implants placed in extraction sockets and healed sites of the anterior maxilla: a retrospective study on 103 patients with 3 years of follow-up," Clinical Oral Implants Research, vol. 28, no. 3, pp. 272–282, 2017
[2]. B. Butler, "Masking buccal plate remodeling in the esthetic zone with connective tissue grafts: immediate implant concepts, techniques," Compendium of Continuing Education in Dentistry, vol. 35, no. 7, pp. 486–493, 2014.
[3]. W. Becker, "Immediate implant placement: diagnosis, treatment planning and treatment steps/or successful outcomes," Journal of the California Dental Association, vol. 33, no. 4, pp. 303–310, 2005.
[4]. C. N. Eliasa, F. A. Rocha, A. L. Nascimento, and P. G. Coelho, "Influence of implant shape, surface morphology, surgical technique and bone quality on the primary stability of dental
[5]. implants," Journal of the Mechanical Behavior of Biomedical Materials, vol. 16, no. 1, pp. 169– 180, 2012..