Series-1 (May-June 2019)May-June 2019 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Toxicological Effect of Ficus musuco Leaf Extract onLiver andKidney Functions Variables of Male Rats |
| Country | : | Nigeria |
| Authors | : | Atasi || Chikanma Onyeoguzoni || Ibegbulem Edna Ogechi || Brown Holy |
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: | 10.9790/3008-1403010107  |
Abstract: Ficus mucuso is a plants whose various parts are employed traditionally in the treatment of different ailments. The decoction of the leaves is commonly used in the management of fever and anemia. The plant is consumed both as medicines and as vegetables with the trust that they are natural and safe without any side effects. Natural does not signify absence of adverse effects. Some plants are said to produce adverse effects that may not be immediate while others may be toxic but no investigation to prove and therefore not documented. The aim of this study........
Key words: Ficus mucuso, toxicity, kidney, liver, plant-extract.
[1] Chukwuma, E.C., Mike, O.S. & Roseline, T.F. (2015). Traditional Medicine and the Future of Medicinal Plants in Nigeria.Journal of Medicinal Plant Studies, 3(4).23-39.
[2] Petrovska, B.B. (2012). Historic review of medicinal plants usage.Pharmacognosy Review, 6(11),1-5.
[3] Khan, K.Y., Khan, M.A., Ahmad, M., Mazani, P., Hussain, I., Fazat, H., Ali, B. &Khan, Z.I. (2011).Ethno-Medicinal Species of Genus FicusL.Used to Treat Diabetes in Pakistan. Applied Journal of Pharmaceutical Sciences, 1(6),209-211.
[4] Alhadi, E.A., Khalid, H.S., Alhassan, M.S., Kabashi,A.S. & Moor, M.O. (2005). Antimicrobial and Phytochemical Screening of Cardia africana in Sudan. World Journal of Pharmaceutical Research, 4(3), 257-267
[5] YazdaniD., TanY.H.,Zainal AbidinM.A.AndJaganathI.B (2011). A review on bioactive compounds isolated from plants against plant pathogenic fungi. Journal of Medicinal Plants Research, 5(30), 6584-6589.
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| Paper Type | : | Research Paper |
| Title | : | Ethanoic Extract of Citrullus Lanatus Seeds Modulates Lipid Variables of Diabetes Induced Rats |
| Country | : | Nigeria |
| Authors | : | Brown Holy || Alozie || Innocent Chinonyerem || Ben-Chioma || AdlineErima |
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: | 10.9790/3008-1403010813 |
Abstract: Approaches to the management of diabetes mellitus is multifaceted. The role of some phytonutrients in the reduction of blood glucose levels is being recognized. Present study investigated the effect of ethanolic extract of Citrullus lanatus seeds on biochemical variables and some haematological indices. Seventy-seven (77) male wistar rats divided into eleven (11) groups of seven (7) rats each were used in this study. Diabetes mellitus was induced in the test animals in groups V – XI by streptozotocin (40mg/kg) after 2 weeks feeding on a High-fat diet (HFD). Group I was normal control rats. Groups II, III and IV were non-diabetic control rats given the vehicles 1% ethanol, corn...........
Keywords: Streptozotocin, diabetes, Citrullus lanatus, lipids, high- fat- diet
[1] Crook, M. A. (2012). Clinical biochemistry and metabolic medicine (8th ed., pp. 176-199). London, England:Hodder& Stoughton.
[2] Muhammad, Y., Saidu, A. Y., Muazu, S., Wali, U., Yaldu, M. H., Abubakar, N. &Bako, H. (2015). Effects of watermelon seed extracts on fasting lipid profile in streptozotocin induced diabetic albino rats. International Journal of Research and Innovations, 3(4), 81-84.
[3] Deshmukh, C. D. & Jain, A. (2015). Antidiabetic and antihyperlipidaemic effects of ethanoicextract of Citrulluslanatus seeds in rats. International Journal of Pharmacy and Pharmaceutical Sciences, 7(10), 232-236.
[4] Omigie, I. O. &Agoreyo, F. O. (2014). Effects of watermelon (Citrulluslanatus) seed on blood glucose and electrolyte parameters in diabetic wistar rats.Journal of Applied Sciences and Environmental Management, 18(2), 231-233 Muhammad et al,2015;
[5] Barbosa-da-Silva, S. Sarmento, I. B., Bargut, T. L. C., Souza-Mello, V. Aguila, M. B. & Mandarim-de-Lacerda, C. A. (2014). Animal models of nutritional induction of type 2 diabetes mellitus. International Journal of Morphology, 3(1), 279–293
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| Paper Type | : | Research Paper |
| Title | : | Assessing the Level of Community Pharmacists' Knowledge about Medicine Inventory Management in Delta State, Nigeria |
| Country | : | Nigeria |
| Authors | : | Austine E Ighorodje || Niyi J Ola-Olorun |
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: | 10.9790/3008-1403011420 |
Abstract: Purpose: To assess the level of community pharmacists' knowledge about medicine inventory management in Delta State. Methods: A cross-sectional descriptive survey of 125 community pharmacists selected using simple random sampling method. Primary data were collected with the aid of a pretested semi-structured questionnaire. Sample size was determined using Taro Yamane's formula for finite population. The questionnaire was designed using simple statements on Likert-type scale with five alternative responses having weighting scores of 0-4. Data collected were analysed using descriptive and inferential statistics at 5% level of significance. Results:The response rate was 96.2% and reliability of the questionnaire was 0.97. Respondents were mostly superintendents (63.2%), computer (63.2%) usage in their premises with 84.8% being used for inventory management purpose. "Record about inventory........
Keywords: Community pharmacy, Inventory management, Stockout
[1] S. Maharaj, M. D'Souza, R. Doodh, N. Kissoon, C. Mohammed, and K.S. Sooklal, Inventory Management Practices in Pharmacies across Trinidad and Tobago. International Journal of Universal Pharmacy and life Sciences, 2(3), 2012, 243-253.
[2] C. C. Orga,Production Management: A Qualitative Approach, (Enugu, Nigeria. Veamarks Publishers,2006.
[3] G. Santhi, and K. Karthikeyan, Recent review on Pharmaceuticals inventory Models. International Journal of Pharm.Tech.Research, 9(5), 2016, 435-443.
[4] M. O. Afolabi, and Oyebisi T. O. Pharmacists' Perceptions of Barriers to Automation in Selected Hospital Pharmacies in Nigeria",Journal of Pharmacy Practice 20(1), 2007, 64- 71.
[5] R. Adepu, andB.G.Nagavi, Attitude and behaviours of practicing community pharmacists towards patient counselling. Indian Journal of pharmaceutical sciences 71(3), 2009, 285-289..
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| Paper Type | : | Research Paper |
| Title | : | Computational studies of plant derived natural compounds with HMG-CoA enzyme through in silico analysis |
| Country | : | India |
| Authors | : | M. Sellappan || M. Rajasekara Pandian || A. Krishnamoorthi || S. Senthilnathan |
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: | 10.9790/3008-1403012125 |
Abstract: Plant products have always been well thought-out for many important metabolic disorders due to its abundant medicinal properties. This study was aimed to identify potent compounds with anti-dyslipidemic property from selected plants and analyse them for their efficiency in binding with HMG-CoA reductive. The 3D structure of HMG-CoA protein was retrieved from protein data bank (PDB ID:3CCZ). Totally four plant derived compounds were selected for docking studies such as 6-gingerol, guajavarin, hesperetin and phloretin. Based on the present study, the maximum docking energy was observed at -100.092kcal/mol with guajavarin and the protein binding sites were identified.........
Keywords: HMG-CoA, Docking, Guajavarin, Phytocompounds.
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