Version-5 (Nov-Dec 2017)
Version 1 Version 2 Version 3 Version 4 Version 5 Version 6
- Citation
- Abstract
- Reference
- Full PDF
Abstract: The main aim of the present work is to prepare, evaluate and compare Lab Made Herbal toothpaste with commercial Herbal toothpastes. In the present study, commercial herbal toothpastes such as Meswak,Dauber red,sudanta have been evaluated for their quality. All the marketed Herbal tooth pastes and Lab Made Herbal toothpasteswere evaluated and complied with the standards specified by the Bureau of Indian Standards. The formulations were evaluated by different tests like pH, spreadability, abrasiveness, foaming ability, fineness,test for F-, Pb and stability studies. All the results showed that Labmade formulation is comparatively equal and rarely better in terms of results than marketed formulation. Hence the selected Labmade formulation was found to be of good quality..
Keywords: Commercial Herbal toothpastes, Bureau of Indian standards, Toothpaste
[1] Jensena JL, Barkvoll P. Clinical Implications of the Dry Mouth:Oral Mucosal
[2] Diseases.Annals of the New York Academy of Sciences. 1998. 842:1, 156–
[3] 162. http://dx.doi.org/ 10.1111/j.1749-6632.1998.tb09643.
[4] AI Kholani, Comparison between the Efficacy of Herbal andConventional Dentifrices on Established Gingivitis, Dental Research Journal (Isfahan). Springer; 2011. 8(2): 57-63.
[5] Ersoy, M; Tanalp, J; Ozel, E; Cengizlier, R; Soyman, M; The allergy of toothpaste: a case report. AllergoletImmunopathol,2008, 36(6),368-70.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Breast cancer is the most common cancer in reproductive-aged women. Most young women diagnosed with breast cancer will undergo chemotherapy. While chemotherapy improves cancer outcomes, it also induces ovarian damage by direct toxicity to the finite pool of ovarian follicles. FSH is secreted by the anterior pituitary and its main work of regulating the growth of the follicles. A low basal FSH level would thus indicate a good ovarian reserve and vice versa.This cohort prospective study was carried out at the Biochemistry Department, College of Medicine, University of Baghdad and at Oncology Clinic,Oncology Teaching Hospital. It included 30 women (25-45 years) who were newly diagnosed to have had breast cancer and underwent chemotherapy (CT) treatment..........
Keywords: FSH, Breast cancer, Chemotherapy, Ovarian reserve
[1]. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127(12), 2008, 2893-2917.
[2]. Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E, Feuer EJ, Thun MJ. Cancer statistics. CA. Cancer J Clin, 54(1), 2004, 8-29.
[3]. Pierce JG and Parsons T F. Glycoprotein Hormones: Structure and Function. Annual Review of Biochemistry, 50(1), 1981, 465-495.
[4]. Fritz MA and Speroff L. Female infertility. In Clinical Gynecologic Endocrinology and Infertility, 8th edition. Philadelphia: Lippincott Williams and Wilkins: 2011; 1137-1190. [5]. Broer SL, Broekmans FJ, Laven JS, Fauser BC. Anti-mullerian hormone: ovarian reserve testing and its potential clinical implications. Hum Reprod Update, 20(5), 2014, 688-701.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: The purpose of designing the floating microbeads based formulation of antidiabetic drugs was to achieve controlled release of the drugs. The floating microbeads based controlled release formulation is expected to aid in reducing the dosing frequency and to increase the gastric residence time. The gastric residence time in present study was induced using the buoyancy characteristics in the gastric fluid. Glibenclamide (glyburide) was selected as a model bioactive which is a second-generation sulfonylurea drug used in lowering blood-glucose in type-II diabetes mellitus. The floating microspheres of Glibenclamide was designed by using polymers including low and high.........
Keywords: Floating Microbeads, Glibenclamide, Alginate, Controlled delivery, Oral route, In vivo study.
[1]. V.Kumar,N.Fausto, Abul K. Abbas, S,Cotran, Ramzi,L.RobbinsandStanley, Robbins and otran Pathologic Basis of Disease (7th ed.). Philadelphia, Pa.: Saunders2005,1194-1195.
[2]. S. Bansal, S. Beg, A. Asthana, B. Garg, G.S. Asthana, R. Kapil, B. Singh, QbD-enabled Systematic Development of Gastroretentive Multiple-unit Microballoons of Itopride Hydrochloride, Drug Delivery,23(2), 2016, 437-451.
[3]. S. Dhiman, A. Asthana, A.K. Tiwary, M. Jindal and G. Shilakari, Development and Evaluation of Novel Cordia Myxa Fruit Gum Based Mucoadhesive Tablets for Gastroretentive Delivery of Losartan Potassium, Journal of pharmaceutical science and research, 7(9)2015, 652-661.
[4]. S. Dhiman, A. Asthana, A.K. Tiwary, M. Jindal and G. Shilakari, Cordia Myxa Polysaccharide-G-Poly(Acrylonitrile) Co-Polymer Based Mucoadhesive Gastroretentive Delivery of Captopril, International Journal of Pharmaceutical Science and Research, 7(1) 2017 1000-13.
[5]. S. Bansal, S. Beg, B. Garg, A. Asthana, G.S. Asthana, B. Singh,Qbd-Oriented Development and Characterization of Effervescent Floating-Bioadhesive Tablets of Cefuroxime Axetil. AAPS Pharmaceutical Science and Technology" 17(5), 2016, 1086-99..
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Malaria is a major cause of illness and death especially among children under 5years. This survey is aim at undertaking a review of malaria intensity among under five malaria positive children in the study area. A retrospective comparative study design was employed using data from Local Health Services from 2012-2016 for under five malaria in Mayo belwa LGA, Adamawa state. 2012 showed moderate malaria to be highest in the month of August (15%) while, severe malaria in September (15.8%). In 2013, moderate malaria was highest in the month of August (19.4%) and severe malaria in the month of September (18.7%). Similarly 2014, showed moderate malaria to be highest in the month of September (20.0%) while severe malaria in October (20.4%). 2015, showed October (19.3%) had the highest..........
Keywords: Malaria, Intensity, Under-five, Transmission, Infection
[1]. Fawole, O.I. &Onadeko M.O. (2001). Knowledge and Mana- ement of Malaria in Under Five Children by Primary HealthCare Workers in Ibadan South East Local Government Area. Nigeria. Post Graduate Medical Journal 8 (1): 1-5
[2]. WHO(1998a) Malaria, WHO Information Fact Sheet No 94 Geneva, W.H.O press officeSwitzerland. : 1 -6
[3]. Lucas, A.O. and Gilles H.M. (1998). A New Short Textbook of Preventive Medicine for the Tropics: Malaria,Great Britain ELBS with Edward Arnold.Publishers :188 - 192..
[4]. Mathers C.D, Mafat D, Inoue M, Rao C, Lopez A.D. (2005) Counting the dead and what they died from: an assessment of the global status of cause of death data. Bull World Health Organ;83:171–77.
[5]. Murray C.J.L, Lopez A.D.(1996)Global Health Statistics: A Compendium of Incidence, Prevalence and Mortality Estimates for Over 200 Conditions.Cambridge: Harvard University Press.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: In the present study, administration of the extract of herbal formulation MEE and MAE at a dose of 2000mg/kg P.O produced a significant reduction in blood glucose level .The anti oxidant activity of herbal formulation is found with a significant growth of CAT and SOD levels compared with normal control and alloxan induced diabetic control animals. Because of presence of free radical scavenging activity of the secondary metabolites in the herbal formulation, MEE and MAE showed significant decrease in levels of SGOT, SGPT, and ALP. In herbal formulation mainly the MEE and MAE showed significant decrease in Cretinine, Urea, Cholesterol and significant increase in HDL-Cholesterol level
Keywords: free radical scavenging activity, Catharanthus roseus, Leucas linifolia, Hypoglycemia, intraperitoneal administration
[1]. Satyanarayana T, P. Dwarakanadha reddy, D.Swarnalatha, Anjana A Mathews, Hypoglycemic effect of a Polyherbal extract on normal and streptazotocin induced diabetic rats, International Journal of pharmacy and pharmaceutical sciences ISSN-0975-1491, Vol2,Issue 3,2010.
[2]. Chandra shekhar Joshi, Ekambaram Sanmuga Priya, and Subramanian VenkataramanHypoglycemic and antilipidperoxidative effects of a Polyherbal formulation, Diakyur, in Experimental animal models. Journal of health sciences, 53 (6) 734-739 (2007).
[3]. Roger Walker,Cate Whittlesea : Clinical Pharmacy and Therapeutics, 4th edition, Churchil living stone 2007; 632
[4]. MycekMJ,HarveRA,ChampaPC,etal,Lippincott'sillustratedReviews;pharmacologyNewyork, Lippincott Willium's & Wilkins 2004; 255-262.
[5]. Rakha PS, Kuttan G, Kuttan R. Antioxidant activity of Brahma rasayana. Indian J Exp Biol 2001 ; 39: 447-452.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Biological monitoring techniques like biochemical variable have become alternative and useful for monitoring environmental quality, water pollution and the health condition of aquatic organisms. Biochemical parameters are frequently used as an indicator of the general state of health and early warming of stress in fish under stressful conditions. Biochemical changes induced by effluent stress lead to metabolic disturbances, inhibition of important enzymes retardation of growth and reduction in the fecundity and longevity of the organism. The fish was exposed to varying levels of the toxicant concentrations using static bioassay to determine the median lethal concentration. The LC50 value is 7.9 per cent the fish was exposed to short and long term periods in sub lethal concentration is 0.79 per cent. Biochemical characteristics like Protein, Carbohydrate and Lipid were estimated......
Keywords: Protein, Carbohydrate, Lipid, effluent and Oreochromis mossambicus.
[1]. Venkatachandrudu, M. And Radhakrishnaiah, K. 2009. Cadmium induced histopathological changes in liver and muscle of the fresh water fish, Labeo rohita . J. Ecotoxic Envir Monit., 19 (3): 265-272.
[2]. Konstantinos C. And Valsamidou. A. V. 2011. Removal of Nickel Copper Zinc and Chromium from Synthetic and industrial waste water by electrocoagulation, Int.J Environ. Sci.1 (5): 698-703.
[3]. Martin, P. Devaprasanth and S.Arivoli, S. 2008. Biochemical study of freshwater fish Catla catla with reference to mercuric chloride.Iran.J.Environ.HLTH.Sci.Eng.,5,109-116.
[4]. Finney, D.J. 1971. Probit analysis, 3rd edition, (London : Cambridge University press), P.20.
[5]. Lowry, O.H., Rose Brough, N.J., Farr, A.L. and Randall, R.J.1951. Protein measurements with the folin phenol reagent.J.Biol.chem., 193: 265-275
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Introduction: Chronic suppurative otitis media (CSOM) is one of the most commonly encountered diseases in otorhinolaryngology practice. Material and method: A total of 70 samples from 64 clinically diagnosed cases of CSOM were included in the study. The bacterial identification and antibiotic sensitivity of the isolates was carried out by automated method. Result: Out of 70 samples 50% (35/70) showed positive bacterial culture. Among 64 patients, 53.12% (34/64) were males and 46.87% (30/64) were females. The commonest bacteria isolated was Pseudomonas aeruginosa45.71% (16/35) followed by Staphylococcus..........
Keywords: Antibiotics, CSOM, Bacterial infection.
[1]. Shenoi P.M. Management of Chronic Suppurative Otitis Media. Scott Brown's text book of Otolaryngology.5th Edition, 1988; 5(3):215.
[2]. Verhoeff M, van der Veen EL, Rovers MM, Sanders EM, &Schilder AGM. Chronic Suppurative Otitis Media: A Review. International Journal of Pediatric Otorhinolaryngology. 2006; 70 (1): 1–12.
[3]. WHO. (2004). Chronic Suppurative Otitis Media Burden of Illness and management options. Report of WHO expert committee. Geneva: WHO, 2004.
[4]. Harshika YK, Sangeetha S, &Prakash R. Original Research Article Microbiological profile of CSOM and their antibiotic sensitivity pattern in a tertiary care hospital. Int.J.Curr.Microbiol.App.Sci. 2015; 4(12): 735–43.
[5]. Dayasena RP, Dayasiri MBKC, Jayasuriya C, &Perera DSC. Aetiological agents in Chronic Suppurative Otitis Media in Sri Lanka. Australasian Medical Journal. 2011; 4(2):101-4.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Bone fractures are caused due to accidents or violent acts caused by others either willfully or negligently. In some cases it may be due to falling or due to pathological reasons or due to osteoporosis. The present survey provides information on the therapeutic properties of 35 plants species belonging to 33 genera and 22 families used for bone fractures by the natives of AP region in Eastern Ghats of India. Information on botanical name, vernacular name, family, part used, mode of drug preparation administration and mode of poultice is provided. Information gathered in this study will act as vital data for scientific community.
Keywords: Bone fractures, ethno medicine, Eastern Ghats of India.
[1]. Anonymous, WHO traditional Medicine Strategy 2002–2005. World Health Organisation, Geneva, Switzerland. (WHO/EDM/TRM/2002.1.). 2002.
[2]. S. Khan, Systems of medicine and nationalist discourse in India. Social Science and Medicine 62, 2006. 2786–2797.
[3]. R.M. Kunwar K.P. Shrestha and R.W. Bussmann, Traditional herbal medicine in far-west Nepal: a pharmalogical appraisal. Journal of Ethnobiology and Ethnomedicine 6, 2010. 35.
[4]. P.A. Cox, M. Balick, The ethnobotanical approach to drug discovery. Scientific American 270, 1994. 82–87.
[5]. Legris and VM. Meher – Homji, The Eastern Ghats: Vegetation and Bilclimatic aspects. Pros. Seminar on Resources development and environment in Eastern Ghats.Andhra University. Waltair. 1982. 1-7.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: The pathogenesis of rheumatoid arthritis (RA), related to a majority of inflammatory and autoimmune disease, is largely due to an inappropriate or inadequate immune response to external factors, among these factors, infectious agents (Cytomegalovirus and Helicobacter pylori)which are considered as candidates of triggering such disease. Method:40 RA patients and 20 healthy control individuals were recruited and tested for Rapid H.pylori and CMV IgG, all RA patients were also tested for quantitative RA IgG, IgM and IgA. Results: the results showed an elevated concentrations of RA IgG , IgM and IgA compared to the normal value of less than 20 U/ml , results also showed no significance differences in the percentage of positive result for H.pylori between RA patient 27.5% and control group 25% , whereas the concentration of CMV IgG in RA patient was significantly higher (110 U/ml) compared to control group (25 U/ml) at (p≤0.01 ) .In conclusion; CMV show more prevalence than H. pylori in the study population of some Iraqi patients..
Keywords: Rheumatoid Arthritis, Cytomegalovirus and Helicobacter pylori.
[1]. Brooks, W.H ., Le Dantec ,C . , Pers ,J. O. , Youinou ,P. ,and Renaudineau ,Y. (2010). Epigenetics and autoimmunity. J. Autoimmun. 34, J207–J219.
[2]. Benedek, T.G.(2006).The history of bacteriologic concepts of rheumatic fever and rheumatoid arthritis. Semin. Arthritis Rheum. 36, 109–123.
[3]. Silman, A.J .,and Pearson, J.E.(2002).Epidemiology and genetics of rheumatoid arthritis. ArthritisRes. 4(Suppl. 3) ,S265–S272.
[4]. Namekawa T, Snyder MR, Yen JH, Goehring BE, Leibson PJ, Wey and CM, et al.(2000). Killer cell activating receptors function as costimulatory molecules on CD4_CD28null T cells clonally expanded in rheumatoid arthritis. J Immunol ;165:1138–45.
[5]. Wagner UG, Koetz K, Weyand CM, Goronzy JJ.(1998) Perturbation of the T cell repertoire in rheumatoid arthritis. ProcNatlAcadSci U S A;95:14447–52.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: A simple , precise and accurate RP-HPLC method was developed and validated for simultaneous estimation of Olmesartan and hydrochlorothiazide in tablet dosage form. Separation was achieved on a reversed-phase Symmetry C18 (4.6 x 150mm, 5m, Make: XTerra) or equivalent using a mobile phase consisting of methanol / acetonitrile (pH 2.5, 65:35, v/v) at a flow rate of 0.8 ml per min and UV detection at 258 nm . The method was validated as per ICH guidelines for linearity , accuracy, precision and robustness. The developed method shows good linearity over the concentration range of 20-80 μg/mL (r2=0.999) for both olmesartan and hydrochlorothiazide . The average percentage recoveries were in the range of 100.0-100.04% and...........
Keywords: Olmesartan , Hydrochlorothiazide , Limits of quantification , limits of detection
[1]. Becket and stenlake, practical pharmaceutical chemistry, part 24th edition CBS publications and distributors, 2005, 157-168.
[2]. P.D. Sethi, HPLC quantitative analysis of pharmaceutical formulations CBS publications and distributors, 1st edition, 2001, 69-70.
[3]. B.K Sharma, instrumental method of chemical analysis, 23rd edition, goal publishers 2004.
[4]. Practical HPLC method development Lloyd R.Snyder, Joseph J. Kirkland, Joseph L. Glajch, second edition, 1, 420-430,686-704.
[5]. Validating chromatographic methods, David M.Bliesner. 1-4.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Background:The synthesis of iron oxide nanoparticles using natural materials with less expensive and less harmful effects the goal in the present time, therefore the biosynthesis of iron oxide nanoparticles (IONPs) using aqueous extract of Iraqi propolis as capping and reducing agent have been done in this research. Material and Method: The formation of IONPs from two types of iron salts using propolis water extract was evaluated. Iron oxide nanoparticles was illustrated by changes in color from brown to black color due to bioreduction of iron salts by propolis extract rich of poly phenols. Result: The synthesized magnetite nanoparticles were characterized by UV – Vis absorption spectroscopy, FTIR, XRD and SEM Techniques .The particles size in IONP formed from mixture ferric and ferrous about 31.714 – 46.20 nm and the IONP synthesis from FeSO4 about 153.45 – 245.17 nm...........
Keywords: Biosynthesis, Iron Oxide Nanoparticles, Magnetite, Propolis
[1]. Christian, P.; Von der Kammer, F.; Baalousha, M.; Hofmann, T. Nanoparticles: Structure, properties, preparation and behaviour in environmental media. Ecotoxicology 2008, 17, 326–343.
[2]. Nochehdehi AR., Thomas S., Sadri M., Afghahi SSS. and Mehdi H. SM." Iron Oxide Biomagnetic Nanoparticles (IO-BMNPs); Synthesis, Characterization and Biomedical Application–A Review" J. Nanomed. Nanotechnol. (2017), 8:1:1 – 9.
[3]. Herlekar M. and Barve.S. "optimization of microwave assisted green synthesis protocol for iron oxid nanoparticles and its application for simultaneous removal of pollutants from domestic sewage" international j of advance res. (2015) (4):331 – 345. Thakur S. and Karak N." One-step approach to prepare magnetic iron oxide/reduced graphene oxide nano-hybrid for efficient organic and inorganic pollutants removal" Materials Chemistry and Physics, (2014)3: 425-432.
[4]. Teje AS. and Pei- Yoongk."synthesis properties and application of magnetic iron oxid nanoparticles ,Prog. Cry. Grow. Charac. Mat , (2009)55: 22 – 45.
[5]. Rieznichenko L., Doroshenko A., Gruzina T., Dybkova S., Polova Z., Ulberg Z. and Ivan C" Iron Nanoparticles' effectiveness for new antianemic preparations development" Nanocon, .(2013) 10:16 – 18.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: The antimicrobial activity of one gel based toothpaste, two normal toothpastes, four herbal toothpastes, two herbal samples was tested against buccal cavity organism. Isolated organism from the selected media has been characterized by using biochemical tests. Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus sp was identified microscopically. The different level of antimicrobial activity was observed by zone of inhibition using disc diffusion and well method.
Keywords: Antimicrobial , Disc diffusion ,Toothpaste , , Zone of inhibition
[1]. Dr. Amitava Bora, Dr. Abhirup Goswami, Dr. Gautam Kumar Kundu, Dr. Biswajit Ghosh,
[2]. 2014: Antimicrobial Efficacy of few commercially available herbal and non-herbal toothpastes against clinically isolated human cariogenic pathogens, Journal of Nepal Dental Association, vol-14.
[3]. Andiara De Rossi, Danielly Cunha Araújo Ferreira, Raquel Assed Bezerra da Silva, Alexandra Mussolino de Queiroz, Léa Assed Bezerra da Silva, Paulo Nelson-Filho, 2014: Antimicrobial Activity of Toothpastes Containing Natural Extracts, Chlorhexidine or Triclosan, Brazilian Dental Journal, ISSN 0103-6440.
[4]. Benly. P, 2015: Comparison of the Bacterial Level by Pre Brushing and Post Brushing using Herbal and Fluoridated Toothpaste. Journal of pharmaceutical sciences and research, ISSN:0975-1459. Vol. 7(6).
[5]. Biju Thomas, Sunaina Shetty Y, Agrima Vasudeva, Veena Shetty, 2011: Comparative evaluation of Antimicrobial Activity of Triphala and commercially available Toothpastes: An in-vitro study, International Journal of Public Health Dentistry, 2(1): 8-12
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Peptic ulcer is disease of the gastric mucosa in which there is erosion and inflammation. The disease is caused by the imbalance between the bicarbonate and acid that is generated in the gastric and duodenal area of the gastrointestinal tract. Ulcers can develop in the esophagus, stomach or duodenum, or at the margin of a gastroenterostomy, in the jejunum, in Zollinger-Ellison syndrome, and in association with a Meckel's diverticulum containing ectopic gastric mucosa. Peptic ulcer disease is one of several disorders of the upper gastrointestinal tract that is caused, at least partially, by gastric acid............
Keywords: Ulcer, PUFA, mucosa, inflammation, carbonic anhydrase, stem cells
[1]. Wroblewski L.E, Peek R.M Jr., Wilson KT.Helicobacter pylori and gastric cancer, factors that modulate disease risk. Clin.Microbiol. Rev. 2010; 23, 713-739
[2]. A Kaur, R Singh, R Sharma, S Kumar. Peptic ulcer: A review or etiology and pathogenesis. Int.Res.Jr.Pharm., 3(6), 34-38, 2012
[3]. Manjari V, Das UN. Oxidant stress, anti-oxidants, nitric oxide and essential fatty acids in peptic ulcer disease. Prostaglandins Leukot.Essent. Fatty Acids. 1998, 59 (6): 401-6
[4]. S. E. Lee, J. W. Lim, J. M. Kim, and H. Kim, "Anti-inflammatorymechanism of polyunsaturated fatty acids in Helicobacterpylori-infected gastric epithelial cells," Mediators of Inflammation, vol. 2014, Article ID 128919
[5]. Segal ED, Lange C. Covacci A et al. Induction of host signal transduction pathways by Helico bacter pylori. Proc.Natl.Acad.Sci.USA. 1997; 94: 7595-7599
- Citation
- Abstract
- Reference
- Full PDF
Abstract: A gradient reversed phase high performance liquid chromatography (RP-HPLC) method has been developed and validated for the determination for related substances of Canagliflozin drug substance. Good chromatographic separation of Canagliflozin from its process and degradation related substances was achieved on Ascentis Express RP-Amide, 150mm × 4.6mm 2.7 i.e stainless steel column 150 mm long, 4.6 mm internal diameter filled with amide groups chemically bonded to porous silica particles of 2.7 m diameter maintained column oven temperature at 30°C. Ammonium acetate buffer is mobile phase A and acetonitrile is mobile phase B. Wavelength for UV detection: 290nm, flow rate: 0.7 ml/min and Injection volume: 10μl. The method suitability checked and validated according to the ICH guidelines for specificity..........
Keywords: Canagliflozin, Related substances, HPLC, Validation
[1]. J. J. Neumiller, J. R. White and R. K. Campbell, Sodium-glucose co-transport inhibitors: progress and therapeutic potential in type 2 diabetes mellitus, Drugs, 70(4), 2010, 377-85.
[2]. S. A. Nisly, D. M. Kolanczyk and A. M. Walton, Canagliflozin, a new sodium- Glucose cotransporter 2 inhibitor, in the treatment of diabetes, Am J Health Syst Pharm, 70, 2013, 311-319.
[3]. Harsharan Pal Singh, Ishpreet Kaur and Gunjan Sharma, Sodium Glucose Co-Transporters-2 (SGLT2) Inhibitors as a New [4]. Class of Anti-diabetic Drugs: Pharmacokinectics, Efficacy and Clinical Significance, Int J Pharm Sci Rev. Res. 33(1), 2015, 40-47.
[5]. B. Haas, N. Eckstein, V. Pfeifer, P. Mayer and M. D.S. Hass, Efficacy, safety and regulatory status of SGLT2 inhibitors: focus n canagliflozin, Nutr Diabetes, 4(11), 2014, e143