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| Paper Type | : | Research Paper |
| Title | : | Bacteremia due to Kocuria rosea in a HIV positive patient with low CD4 count: A case report |
| Country | : | India |
| Authors | : | Biswajeet Sahoo || Sanjeeb Sharma || Sudipta Naorem || Khuraijam Ranjana Devi || Kh. Sulochana Devi || Damrolein S. |
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: | 10.9790/3008-09630103  |
Abstract: Introduction: Gender Kocuria includes 11 species, of which to date only K. rosea varians K. and K. kristinae, are pathogenic, although infrequently cause disease in immunocompromised patient Materials and Methods: The blood sample was collected from the patient and inoculated into the Brain Heart infusion biphasic media and after positive growth it was subjected to phenotypic identified by Vitek-2. Objectives: To detect the presence of systemic blood stream infection in the immunocompromised patient. Results: There was positive growth on the Brain Heart biphasic media and then when it was subjected to Vitek-2 it was found to be Kocuria rosea with 97% probability and excellent identification confidence Conclusions: The present case signifies the importance of Kocuria rosea as a important cause of bacteremia in immunocompromised patients though it is very rare.
Keywords: Blood stream infection, immunocompromised, bacteremia.
[1]. Stackebrandt E, Koch C, Gvozdiak O, Schumann P. Taxonomic dissection of the genus Micrococcus: Kocuria gen. nov., Nesterenkonia gen. nov., Kytococcus gen. nov., Dermacoccus gen. nov. and Micrococcus Cohn 1872 gen. emend, Int J Syst Bacteriol 45(4), 1995, 682–92.
[2]. Altuntas F, Yildiz O, Eser B, Gundogan K, Sumerkan B, Cetin M, Catheter-related bacteremia due to Kocuria rosea in a patient undergoing peripheral blood stem cell transplantation. BMC Infect Dis , 4, 2004,62.
[3]. Basaglia G. Catheter-related bacteremia due to Kocuria kristinae in a patient with ovarian cancer, Journal Clin Microbiol, 40, 311–313.
[4]. Lee JY. 2009. Two cases of peritonitis caused by Kocuria marina in patients undergoing continuous ambulatory peritoneal dialysis, Journal Clin Microbiol, 47,2009, 3376 –3378
[5]. Lai CC. Catheter-related bactaeremia and infective endocarditis caused by Kocuria species, Clin Microbiol Infect, 17, 2010, 190 –192.
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| Paper Type | : | Research Paper |
| Title | : | Characteristics of Patients with Thalassemia Major in AL-Muthana Governorate and description of their Blood groups influences, consanguineous marriage problem. |
| Country | : | Iraq |
| Authors | : | Mohamed Maroof Middib || Fadil Abass Al- Moktar || Abdul Kareem S. Saqban |
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: | 10.9790/3008-09630408 |
Abstract: Thirty patients, twenty two were males, eight were females and two ware normal control, aging between one year and twenty two year. Twenty nine (99%) patients, were consanguineous their parents are relative one was normal merge and studied in the Feminine and Children Hospital of Al Samawa/Iraq. All patients had spleenomegaly and Hepatomegaly with teeth deformities. Thirteen males with cardiomegaly and SIX females with bronchopneumonia. All patients with low hemoglobin (less than 9.13 g/dl compared to the average control which was 10.72-14.76g/dl
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| Paper Type | : | Research Paper |
| Title | : | Antibiotic resistant pattern of wound isolates of Staphylococcus aureus |
| Country | : | India |
| Authors | : | Kalpana Chaudhari || Harish Kumar Bajaj || Chhabu Kala Rai |
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: | 10.9790/3008-09630915 |
Abstract: Rapid resistance to most of the antibiotics has been problematic in therapy of Staphylococcal infection. Methicillin resistance Staphylococcus aureus was cured by vancomycin earlier. Later on vancomycin resistance S. aureus was emerged. The study was attempted to observe the antibiotic resistance pattern of wound infecting S. aureus. Altogether 55 S. aureus isolates were studied from 253 wound samples. Among them, 19 (34.54%) exhibited complete resistant to methicillin. In context of vancomycin, 4 (7.27%) were detected as resistant and 27(49.01%) appeared to be resistant to multiple drugs.
[1]. F.D. Lowy, Antimicrobial resistance: the example of Staphylococcus aureus. Journal of Clinical Investigation, 111, 2003, 1265–1273.
[2]. J Omololu-Aso, D.O. Kolawole, O.O. Omololu-Aso and S.O. Ajisebutu, Antibiotics sensitivity pattern of staphylococcus aureus from fomites in the Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) Nigeria. International Journal of Medicine and Medical Sciences, 3(2), 2011, 32-36.
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[5]. A.P. Magiorakos, A. Srinivasan, R.B. Carey, Y. Carmeli, M.E. Falagas, C.G. Giske, S. Harbarth, J.F. Hindler, G. Kahlmeter, B. Olsson-Liljequist, D.L. Paterson, L.B. Rice, J. Stelling, M.J. Struelens, A. Vatopoulos, J.T. Weber and D.L. Monnet, Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clinical Microbiology and Infection, 18, 2012, 268–281.
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| Paper Type | : | Research Paper |
| Title | : | Genetically Modified Birds |
| Country | : | Nigeria |
| Authors | : | Chidinma Adanna Levi || Daniel Don Nwibo || Christian Onyeka Chukwuka || Chidimma Linda Mbadugha |
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: | 10.9790/3008-09631629 |
Abstract: Genetic engineering, which is synonymous to genetic modification, is the designed alteration of the genetic make-up of an organism and it is the basis for modern biotechnology. on the other hand, biotechnology is the application of science in production of goods and services using biological agents. The cell which is the functional unit of life contains two kinds of nucleic acids: Deoxyribonucleic acid (DNA) and the Ribonucleic acid (RNA). While the DNA is the genetic material, the RNA functions in protein synthesis. The tools and method for genetic modification include; gene insertion, gene deletion and gene regulation. Vectors are the biological vehicles used to transport DNA into host cells and without them, the whole process will be almost impossible.
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[7]. S. Mader, Biology, Mc GrawHill Companies, 946 Pages, 2011.
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| Paper Type | : | Research Paper |
| Title | : | Effect of dietary deficiency of vitamin B6, vitamin B12 and folic acid on the development of coronary artery disease in adult Indian male patients |
| Country | : | India |
| Authors | : | Smritikana Biswas || Supriya Kumar Misra || Prithwiraj Mukherjee || Chandradipa Ghosh |
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: | 10.9790/3008-09633035 |
Abstract: The present study was conducted to find out the correlation of dietary deficiency of vitamin B6, vitamin B12 and folic acid on development of coronary artery disease (CAD). This study was carried out on 172 male patients of age group between 45-65 years having both genetic and non-genetic background for CAD from Kolkata, India. Present study showed that BMI, SBP, DBP, LDL-c, triglyceride, total cholesterol, fasting and post prandial blood glucose level, homocysteine, CPK and CPK-MB enzyme levels were higher while HDL-c, LVEF and hemoglobin levels were lower than recommended normal values in both subject groups. Daily consumption of carbohydrate, vitamin B12, vitamin B6 and folic acid levels of both subject groups were found to be lower while consumption of fat was higher than recommended values. Present study showed that there was a significant correlation between intake of vitamin B6, vitamin B12 and folic acid and risk factors for CAD in both groups. All these findings indicate that folic acid, vitamin B6 and vitamin B12 deficiency may have influence in developing risk for CAD.
[1]. R. Lozano, Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010, Lancet, 380, 2012, 2095–2128.
[2]. C. James, Risk factors for coronary artery diseases: A study among patients with ischemic heart disease in Kerala, Heart India, 1, 2013, 7–11.
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[4]. R. Gupta and V.P. Gupta, Meta–analysis of coronary heart disease prevalence in India, Indian Heart Journal, 48, 1996, 241–245.
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| Paper Type | : | Research Paper |
| Title | : | Preliminary Phytochemical Analysis of Pentapetes phoenicea L. |
| Country | : | India |
| Authors | : | Yawalikar N. || Bhowal M. || Rudra J. |
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: | 10.9790/3008-09633639 |
Abstract:The present study was undertaken to study the phytochemicals present in Pentapetes phoenicea from the family Sterculiaceae. In nature the plant grows in moist soil. It can also be grown under the shade of trees as well as in open sunny areas. For preliminary phytochemical analysis different solvents like petroleum ether, chloroform, acetone, methanol and distilled water were used. It revealed the presence of alkaloids, flavonoids, saponins, steroids, phenolics, coumarins and triterpenoids in leaf, stem and root extracts.
Key words: Phytochemicals, Pentapetes phoenicea, alkaloids, flavonoids, phenolics.
[1]. Arlario M, Coisson JD, Travaglia F, Varsaldi F, (2005) Antioxidant and biological activity of phenolic pigments from Theobroma cacao hulls extracted with supercritical CO2. Food Research Int., 1009-1014.
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[5]. Das AK and Bhattacharjee AK (1970) A systemic approach to phytochemical screening Tropical Science, 12: 54-58.
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| Paper Type | : | Research Paper |
| Title | : | Comparative Studies of Ethanolic and Aqueous Extracts of Bambusa Vulgaris for Anthelmintic Activities in Infected Rabbits |
| Country | : | Nigeria |
| Authors | : | Barnabas, B. B. || Olutimayin A. T || Danazumi, N. Jiya A. G. || Adebayo, O. J. |
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: | 10.9790/3008-09634043 |
Abstract: Ethanolic and aqueous extracts of Bambusa vulgaris leaf were comparatively screened for anthelmintic activities; ethanolic extract appeared to be more potent in expelling the ova of Ascaris worm and the treated rabbits showed rapid weight gain with a mean value of 0.25kg after treatment as against 0.21g during infection than aqueous extracts. These suggest that they could serve as an alternative source of anthelmintic agent to patented anthelminthic drugs.
[1]. Al-Shailbani; Phulan, M.S. and Qureshi, S. (2008). Ovicidal and Larvicidal Properties of Adhatoda vasica Extracts against Gastrointestinal Nematodes of Sheep in Vitro. Veterinary Journal. 28(2): 79 - 83
[2]. Barnabas, B.B.; Mann, A.; Ogunrinola, T.S. and Anyanwu, P.E. (2011). Screening for Antheimuthis Activities from Extracts of Zanthoxylcom Zanthexyloides, Neocarya Macrophylla and Celosia Laxa against Ascaris Infection in Rabbits. International Journal of Applied Research in Natural Prodcuts. Vol. 3(4), Pp. 1 – 4
[3]. Charlier, J.; Johan, H.; Georg, V.S.M. Pierce, D. and Jozef, V. (2009). Gastrointestinal Nematode Infection in Adult Dairy Cattle; Veterinary Parasitological 164: 70 – 79
[4]. Cheesbrough, M. (1999). District Laboratory Practice in tropical Countries Part 1: Low Price Cambridge edition.
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| Paper Type | : | Research Paper |
| Title | : | The Use of Ageratum Conyzoides L. [Asteraceae] As A Therapeutic Measure In The Treatment Of Breast Myiasis Sores In Rural Women And Associated Bacteria. |
| Country | : | India |
| Authors | : | Ogbalu, O. K. || Williams, J.O. |
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: | 10.9790/3008-09634450 |
Abstract: This study reports for the first time on the use of ethanolic extract of Ageratum conyzoides in women with breast myiasis. A total of fifty rural women were examined [ages 18-62 years old] and 17.25% had breast myiasis at the fishing settlements at Okoikri and Oyorokotor of Rivers State Nigeria. Women with cutaneous breast myiasis were treated with ethanolic leaf extracts of Ageratum conyzoides. Different numbers of maggots were extracted from the breasts and 92.7% of nursing mothers had their sores healed after the application of ethanolicic extract of A. Conyzoides. After the extraction of larvae of Cordylobia anthropophaga, the application of ethanolic extract of A.
1]. Abbey, S.D.(2007) Foundation in medical Mycology (4th edn.).Kenalf Publication, Port Harcourt, Nigeria.22-30.
[2]. Anonymous (1994).Annual Book of ASTM Standards. Water and Environmental Technology,11:2(Water 11).520-523,ASTM,Philadelphia,PA.
[3]. Cheesebrough,M.(2000). District Laboratory Practice in Tropical Countries ,Part 2.Cambridge Univ.Press;UK,35-38,62-69.
[4]. Frazier,W.C. and Westhoff,D.C. (2003). Food Microbiology,4th edition . Mcgraw-Hill Publishing Company Ltd. 66-67.
[5]. Harrigan W.F. and mccance M.E.(1990). Laboratory Method in Food and Dairy Microbiology, Academic Press,London.
[6]. Ita, S.O., Akpanyung, E.O., Umoh, B.I., Ben E.E. and Ukafia, S.O. (2009) Acetaminophen Induced Hepatic Toxicity: Protective Role of Ageratum conyzoides. Pakistan Journal of Nutrition, 8:928-932.
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| Paper Type | : | Research Paper |
| Title | : | Study of Genetic Polymorphisms of Vascular Endothelial Growth Factor in Women with Recurrent Abortion |
| Country | : | Egypt |
| Authors | : | Rizk El-baz || Mohamed H. Bedairy || Ahmed M. Saad || Mohamed S. El-gareeb |
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: | 10.9790/3008-09635155 |
Abstract: Vascular endothelial growth factor (VEGF) regulates endothelial cell proliferation, migration and differentiation. VEGF plays a critical role in angiogenesis during placenta formation. We investigated whether VEGF gene polymorphisms are associated with recurrent pregnancy loss. One hundred women with recurrent abortion and 100 control women with live-born children were recruited from healthy Egyptian women. VEGF gene polymorphisms were assessed with PCR-RFLP analysis of DNA samples obtained from peripheral blood. DNA fragments were investigated by using appropriate primers. SNP scanning was performed using MnII, BgIII, BsfmI, and NIaII restriction enzymes for 1154 G/A, 2578 C/A, 634 C/G, and 936 C/T polymorphisms, respectively. Recurrent abortion among Egyptian women was strongly associated with the mutations related to VEGF gene polymorphism. Interestingly, VEGF 1154 G/A, 2578 C/A and 634 C/G mutation frequencies were significantly higher different between the controls and women with recurrent abortion. However, the 936 C/T was not significantly in women with recurrent abortion.
Key words: Polymorphisms; Recurrent abortion; VEGF.
[1]. Farquharson RG, Jauniaux E, Exalto N. Updated and revised nomenclature for description of early pregnancy events. Hum Reprod. 2005; 11: 3008–3011.
[2]. 2. Jauniaux E, Farquharson RG, Christiansen OB, Exalto N. Evidence-based guidelines for the investigation and medical treatment of recurrent miscarriage. Hum Reprod. 2006; 11: 2216–2222.
[3]. Silver RM, Branch DW, Goldenberg R, Iams JD, Klebanoff MA. Nomenclature for pregnancy outcomes: time for a change. Obstet Gynecol. 2011; 11: 1402–1408.
[4]. Younis JS,Ohel G,Brenner B, Ben-Ami M.Familial thrombophilia-the scientific rationale for thrombophylaxis in recurrent pregnancy loss? Hum Reprod 1997;12:1389-90.
[5]. Raziel A, Kornberg Y, Fridler S Schachter M, SelaBA, Ron-EL R. Hypercoagulable thromothilic defects and hyperhomocysteinemia in patient with recurrent pregnancy loss. Am J Reprod Immunol 2001;45:65-71.
[6]. Yamada H, Kato EH, Kobashi G, Ebina Y, Shimada S, Morikawa M, et al. Recurrent pregmancy loss: etiology of thrombophilia. Semin Thromb Hemost 2001;27:121-9.
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| Paper Type | : | Research Paper |
| Title | : | Effect of Nutritional Intervention Treatment for Ovx Induced Osteoporosis on Oxidant-Antioxidant Status in Female Wistar Rats |
| Country | : | India |
| Authors | : | Sakshi Siriah || Swati Kotwal |
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: | 10.9790/3008-09635662 |
Abstract: Postmenopausal osteoporosis in women is the result of decline in synthesis of ovarian hormone estrogen, leading to reduced bone mass and increased bone turnover. Estrogen deficiency also affects antioxidant status in the body by production of reactive oxygen species. Continuous synthesis of reactive oxygen species damages the bone and enhances osteoclastogenesis. Irrespective of the therapy followed, Calcium, Vitamin D and Zinc are prescribed for osteoporosis. Osteoporosis being multifactorial disease in nature, only calcium and vitamin D supplement fails to make up for the bone loss. We addressed this problem by formulating treatments targeting various factors involved in the progression of osteoporosis by supplementing amino acids, genestein isoflavones and Vitamin K2. Increased oxidant status and decreased antioxidants enzymes were observed in OVX group followed by reversing effect in treatment groups enabling to understand that bone mineralizing nutrients and minerals seem to show positive effect on ovariectomy induced oxidative damage.
[1]. M. A Sanchez-Rodriguez, M. Ruiz-Ramos, E. Correa-Munoz and V. Manuel Mendoza-Nunez, Oxidative stress as a risk factor for osteoporosis in elderly Mexicans as characterized by antioxidant enzymes, BMC Musculoskeletal Disorders, 8:124 doi: 10.1186/1471-2474-8-124 (2007).
[2]. R. Pacifici, Postmenopausal Osteoporosis: How the Hormonal Changes of Menopause Cause Bone Loss, (3rd edition) Osteoporosis, (Elsevier, Inc. 2008), pg 1041-1054.
[3]. M. Almeida, L. Han, Skeletal Involution by Age-associated Oxidative Stress and Its Acceleration by Loss of Sex Steroids, Journal of biological chemistry, September 14; 282(37), (2007) 27285–27297.
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[6]. M. J. Steinbeck, W.H. Appel, A J. Verhoeven, M. J. Karnovsky, NADPH-Oxidase Expression and In Situ Production of Superoxide by Osteoclasts Actively Resorbing Bone, The Journal of Cell Biology,126, (1994) 765-772.
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| Paper Type | : | Research Paper |
| Title | : | Molecular Docking Studies of Shc1 Protein: A Drug Target to Treat Obesity |
| Country | : | India |
| Authors | : | Shobha Shouche || Sachin Rahangdale || , Ravikant Yadav || Harshad Sharma |
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: | 10.9790/3008-09636368 |
Abstract: Scientists recently identified the important role of SHC1 gene expression in causing obesity. SHC1 protein has been found to be highly active in fatty tissues. It could help to develop medicines to treat obesity and related diseases such as heart disease, diabetes, cancer etc. In this present work, based on protein-ligand interaction studies, we proposed interacting domain for SHC1 (PDBID: 1N3H) and further the interacting domain was chosen to screen with a set of natural compounds. At last the potent lead molecules with good docking score were screened for their ADMET properties. The best inhibitor has been reported here.
Key words: Inhibitor, Ligand, Docking, Interaction, Screen
[1]. Supernatural database: http://bioinf-applied.charite.de/supernatural_new/index.php
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| Paper Type | : | Research Paper |
| Title | : | A Simple Rp-Hplc Method for Simultaneous Estimation of Paracetamol and Metoclopramide. HCl inTablet Dosage Form |
| Country | : | India |
| Authors | : | Vamshikrishna. G || Neelima. M || Bhavani. M || Sreekanth. G || Shobha Rani. S |
|
: | 10.9790/3008-09636978 |
Abstract:A simple, rapid, specific, precise and accurate reverse phase high performance liquid
chromatographic (RP-HPLC) method has been developed and validated for the simultaneous estimation of
Paracetamol and Metoclopramide.HCl in tablet dosage form. The chromatographic separation was
achieved on AM Chemteq C18 (250mm x 4.6mm, 5μ) column at a detector wavelength of 220nm using an
isocratic mobile phase comprising a mixture of Methanol: 0.5% Ammonium dihydrogen orthophosphate
buffer (pH: 3) (35:65v/v) pumped at a flow rate of 1.0ml/min. Paracetamol and Metoclopramide.HCl
eluted at the retention times of 4.35 and 7.5min respectively. The method was validated with respect to
parameters such as specificity, linearity, precision, accuracy, robustness, limit of detection, limit of
quantification, system suitability. The proposed RP-HPLC method can be used for the estimation of these
drugs in tablet dosage form.
Keywords: HPLC, Paracetamol, Metoclopramide.hcl, Validation
[1]. David AW, Thomas LL. FOYE'S principles of medicinal chemistry. 5th ed. Maryland: Lippincott Williams & Wilkins; 2002.
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[5]. Bhavsar AS,Talele GS, Fursule RA, Surana SJ. Simultaneous estimation of Paracetamol and Valdecoxib in tablet formulation by RP-HPLC method. Indian Journal of Pharmaceutical Sciences, 68, 2006,675-677.
[6]. Karthik A, Subramanian G, Ranjith Kumar A, Udupa N. Simultaneous estimation of Paracetamol and Domperidone in tablets by RP-HPLC method. Indian Journal of Pharmaceutical Sciences, 69, 2007, 142-144.
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| Paper Type | : | Research Paper |
| Title | : | In Silico Target Deconvolution of Curcumin (Diferuloylmethane) Against Rubella Virus (RUBV) and Hepatitis Delta Virus (HDV) |
| Country | : | India |
| Authors | : | Mansi.J. Shah || Roopa. L1 || Pravin Kumar.R |
|
: | 10.9790/3008-09637984 |
Abstract: Recent studies have been done on the antiviral properties of Curcumin. In relation to this Curcumin has been docked against the proteome of the ssRNA(+) Rubella virus (RUBV) and ssRNA(-) Hepatitis D virus (HDV) to identify the proteins which may act as targets for curcumin. The docking studies show low binding energies of curcumin with Non-structural polyprotein of RUBV with Ki value as low as 2.04 μM and Small delta antigen of HDV with Ki value 53.04 μM. The study has identified the same proteins to be the susceptible target in RUBV and HDV for binding of curcumin or its bioconjugates to combat the virus.
Keywords: Autodock, I-TASSER, Viral zone, Non-structural polyprotein, Small delta antigen
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| Paper Type | : | Research Paper |
| Title | : | In Vitro Anticancer Activity Of Quercetin Isolated From Carmona retusa (Vahl.) Masam on Human Hepatoma Cell Line (Hepg2) |
| Country | : | India |
| Authors | : | Chandrappa C.P || Govindappa M || Anil Kumar N.V || Channabasava R || Sadananda T. S || Sharanappa P. |
|
: | 10.9790/3008-09638591 |
Abstract: Quercetin was isolated from an ethanol extract of Carmona retusa (Vahl.) Masam and was analyzed for its anticancer activity on HepG2 cell lines by MTT assay, Hoechst 33342 staining and Caspase-3 colorimetric assay. Plant extract yield of flavonoid quercetin from Carmona retusa (Vahl.) Masam showed significant and concentration-dependent anticancer activity at 100 μg/ml and 80 μg/ml doses after 24 and 48 h of treatment on HepG2 cell line in MTT assay, significant cell apoptosis have shown at 53μg/ml concentration of extract yield of flavonoid quercetin from Carmona retusa (Vahl.) Masam in Hoechst 33342 staining and a significant activation of caspase-3 observed at 100 μg/ml of extract yield of flavonoid quercetin from Carmona retusa (Vahl.) Masam after 24 h and even 48 h of incubation. Our findings suggesting that the plant extract yield of flavonoid quercetin from Carmona retusa (Vahl.) Masam could be used as a promising anticancer agent.
Key Words: Carmona retusa, anticancer, HepG2 cell lines, MTT assay, Hoechst 33342, Caspase-3 colorimetric assay.
[1] P Vishnu Priya, K Radhika, R Siva Kumar, M Sri Ramchandra, Y Prameela Devi and A.S Rao, Evaluation of anti-cancer activity of Tridax procumbens flower extracts on PC- 3 cell lines, Pharmanest - An International Journal of Advances in Pharmaceutical Sciences, 2, 2011, 28-30.
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| Paper Type | : | Research Paper |
| Title | : | Anti Snake Venom Potential of Securidaca longepedunculata Leaf and Root Bark on Spitting Cobra (Naja nigricollis Hallowel) in Envenomed Wister Rats |
| Country | : | Nigeria |
| Authors | : | Junaidu Sanusi || Kasim Shehu || Abdulhadi Bawa Jibia || Iliya Mohammed || Sanusi Liadi |
|
: | 10.9790/3008-09639296 |
Abstract: This study was undertaken to investigate the anti snake venom potential of aqueous extracts of Securidaca longepedunculata leaves and root bark extracts against Snake venom of Spitting cobra (Naja nigricollis). The venom of Naja nigricollis snake was used to test the anti snake venom efficacy of the extracts, using experimental rats. The anti snake venom activity revealed that root bark extract are able to neutralize snake venom at 300mg/kg body weight with 100% survival. And the leaf extract recorded lower anti venom activity of 0% at 200mg/ml survival and 33.33% of mortality at 300mg/ml. But in the combined root bark and leaves extract it shows higher activity of 66.67% survival at 300mg/ml and 33.33% mortality at 200mg/ml. The result indicate that phytochemical constituents of S. longepedunculata leaves and root bark extracts could also be used to enhance the treatment of the snake venom or bites as it shows a significant anti venom effect (p<0.05) against Naja nigricollis venom. Sub-acute toxicity and determination of LD50 of the plant extracts should be carried out and to enlighten pharmacists on the use of such plant extract for the treatment of various snake bites.
Key words: Aqueous extract, Envenomation, Mortality, Phytochemical, Securidaca longepedunculata, Snake venom.
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| Paper Type | : | Research Paper |
| Title | : | Sorption and Removal of Pb+2 Ions from Aqueous Environment Using Okra Stem Derived Cellulose Material |
| Country | : | Nigeria |
| Authors | : | Okorie D. O |
|
: | 10.9790/3008-09639799 |
Abstract: The removal of Pb2+ ions from aqueous environment using okra derived cellulose biomass has been investigated. Percent sorption of Pb2+ ions in waste water decreased with increase in concentration of Pb+2 in waste water but increased with increase in adsorbent weight of the biomass. Percent sorption of Pb2+ is time dependent; showing a maximum at 10 minutes contact time. Keywords: Okra derived biomass, pb2+ ions
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| Paper Type | : | Research Paper |
| Title | : | Relationship between Trichomonas vaginalis and malignant cell in cervix in Babylon city |
| Country | : | Iraq |
| Authors | : | Maher A. Al-Quraishi || Raflaa S.H. Hussian || Sura I. A. Jabuk || Susan I. A. Jabuk |
|
: | 10.9790/3008-0963100102 |
Abstract: Samples were collected during the period from 1/2 to 15/6 from some private clinics in the province of Babylon of women who suffer from frequent infections in the genital tract and urinary for the purpose of knowing the relationship between parasite Trichomonas vaginalis and Malignant cells .Current study included (250) samples cervical swap , the samples were examined by a wet swab and centrifugation, also examined samples mediated Pap smear was incidence of (20%) mediated wet swab and (22%) mediated centrifuge without significant differences while we did not notice the presence of malignant cells mediated by Pap smear. The study involved measuring the rate of iron and calcium in the blood, was the rate of iron (55.30 μg / dl), while the rate of calcium was (9.10 mg / dl) without significant differences.
Key words: Trichomonas vaginalis; Iron; Calcium; Pap smear.
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