iosr-JPBS   Volume-15 ~ Issue-3 ~ May-June 2020

Abstract: According to the latest World malaria report, there were 228 million cases of malaria in 2018 compared to 231 million cases in 2017. The estimated number of malaria deaths stood at 405 000 in 2018, compared with 416 000 deaths in 2017. Nigeria is a high endemic country of malaria. This study is on the prevalence of malaria in two hospitals in Igbesa, Ogun State. The study was carried out between May and June 2019. A total of one hundred (200) individual were examined. Microscopic examination was carried out on the thick film prepared. The overall total prevalence showed a total number of 85 (85%) positive for malaria. The patients of age group 11-20 years had the highest rate of infection (100%) in both hospitals. Also adult ages 21-30 years of age had (85%) prevalence of malaria.Percentage of students infected with malaria was 84.5% while trader and factory workers had prevalence of 85% and 88.8% respectively. There is need of rigorous control measures and enlightens campaign to further educate occupants of this area on malaria transmission. Campaign, Malaria, Patients.Igbesa

Abstract: Background: The recent outbreak of COVID-19 in different states of the India is a major concern for all the administrative units of our country. The effect of lockdown and social distancing plays a major role for COVID-19 spread and recovery percentage. Forecasting COVID-19 patients has recently become the focus of numerous researchers across the globe. Materials and Methods: The current study aims to develop an auto-regressive integrated moving average (ARIMA) model to predict the COVID-19 patients raise, recovery and death in India based on the daily data obtained from the Indian Govt from 30th........

Key Words : COVID-19, Forecasting, Lockdown, Time series modelling, ARIMA, Social distancing

Abstract: The present study aims to explore antimicrobial potential of folklore medicinal plants growing in and around KODADagainst certain human pathogens. Human pathogens include gram positive bacteria, gram negative bacteria and fungi. In principle the process involved in the antimicrobial screening is similar to that of the isolation of antibiotic and /or isolation of enzyme from microorganisms. The isolation of antibiotics includes the isolation and characterization of microorganisms, culturing of organisms in suitable media, its antagonistic activity band finally the characterization of the antibiotic. The isolation of antibiotic or the enzyme is not possible in two months' time. Therefore, we took up the research "ANTIMICROBIAL SCREENING OF SOME FOLKLORE MEDICINAL PLANTS OF TRADITIONAL USE GROWING IN AND AROUND KODAD"......

Keywords: Folklore Medicinal plants, Microorganisms, MIC, Catalase Coagulase, Antimicrobial activity, carbohydrates, Proteins, whole plant, Root,Flower.

Abstract: Immune system consists of collection of cells, different processes, and chemicals that constantly defends the body against invading pathogens, which includes viruses, bacteria and other toxins. Keeping the immune system healthy and strong year-round is the key to prevent infection and diseases, this can be done by making healthy life style choices by consuming nutritious food and getting enough amount of sleep and exercise, these are the most important ways to boost the immune system. Immune system can be weakened due to smoking, alcohol consumption, and poor nutrition, temporary acquired immune deficiencies caused due to few medicines, example chemotherapy to treat cancer, also post organ transplantation. AIDS is acquired viral infection that destroys important....

Keywords: COVID-19, Immunity, Nutrition, Vitamin C, Infections

Abstract: Introduction : The length of hospital stay has been used as a checkmark in the quality of healthcare provided. While various factors can influence the number of days ASA grade has been of major part in post-operative patients. The choice of right post-operative analgesia used has been associated with improved patient outcomes throughout the world. Evaluating its effect on length of hospitalization can help determine the right analgesic to an extent. Materials and methods : 94 patients from orthopedic ward who were about to undergo surgery and under ASA grade III or below were enrolled in a prospective observational study based on inclusion and exclusion criteria. Post-surgery the patients were divided into two groups based on analgesic administered. The length of hospitalization was recorded. Statistical analysis was done using SPSS v 22.0 Results :The length of stay (....

Keywords: Length of hospital stay, post-operative, ASA grade, analgesic.

Abstract: Diabetes mellitus (DM) is a chronic, metabolic disease considered as one of the five leading causes of death in the world. It affects more than 422 million people worldwide and in the next 10 years, may affect five times more people than it does now. Medical authorities such as World Health Organization encourage research works on herbal medicines to actualize alternatives for its treatment, since oral anti-diabetic agents have side effects in the long term. To date, a vast number of plants have been evaluated for their anti-diabetic potencies. Although, Nigeria has a rich flora and an approximately 4.9% prevalence of diabetes mellitus, onlyfew ethno-botanical studies have been conducted on the possibilities of herbal treatment of diabetes. The aim of this study is to re-evaluate the modern approach to the management of diabetes in Nigeria. Thus, a case study of selected, approved health centers in Ipokia LGA of Ogun State, Nigeria was embarked on as to proffer herbal alternative to treatment......

Key words: diabetesmellitus, patients, hyperglycemic agents, herbal medicine.

Abstract: Résumé: La leucémie myélomonocytaire juvénile (LMMJ) est un syndrome frontière myélodysplasique/myéloprolifératif touchant les jeunes enfants. Il s'agit d'une hémopathie rare et difficile à diagnostiquer vue la ressemblance des signes cliniques et des données du myélogramme avec les autres syndromes myéloprolifératifs. Cependant, la monocytose persistante, le myélogramme et la cytogénétique permettent de confirmer le diagnostic. Nous décrivons un cas de leucémie myélomonocytaire juvénile chez un garçon de 4 ans, qui a présenté un syndrome méningé, une splénomégalie avec une hyperleucocytose. Le diagnostic a été fait à partir d'un frottis sanguin périphérique et médullaire complété par une étude caryotypique. En raison de la rareté de sa survenue, il a été jugé intéressant de rapporter ce cas de leucémie myélomonocytaire juvénile et de rappeler à travers une revue de la littérature certaines caractéristiques intéressantes de cette entité spécifique de la population pédiatrique.

Abstract: Willebrand disease (WD) is the most common constitutional haemorrhagic pathology; due to a quantitative or qualitative abnormality of von Willebrand factor (VWF). Its main symptomatology is mucocutaneous haemorrhages or bleeding caused by trauma or an invasive procedure, but it can also lead to gastrointestinal haemorrhages and haemarthrosis in the most severe forms. Von Willebrand factor (VWF) is a multimeric glycoprotein essential for primary hemostasis. It also carries clotting factor VIII (FVIII), prolonging its half-life and concentrating it in the damaged endothelium. Identification of VWD patients is now possible in many hemostasis laboratories thanks to....

Keyword: Maladie de Willebrand, Facteur de Willebrand, Diagnostic biologique

Abstract: One of the ways to handle of hyperglycemia cases is by developing herbal medicines. In this case, research has been carried out on "the effectiveness of inai leaf extract (Lawsoniainermis Linn) and noni fruit extract (Morindacitrifolia L.) asantihyperglycemic against to rats was induced alloxan".The study used a laboratory experimental method and a completely randomized design (CRD) with a normal control group (physiological saline), a control group that was treated with alloxan (150 mg/kg, peritoneal injection/i.p), alloxan group (150 mg/ kg.ip)+standard drug (metformin) (5 mg/kg, po), alloxan group (150 mg/kg.ip)+henna and noni extract (1:2 = 125:800 mg/kg body weight), alloxangroup+henna extract and noni (1:1 = 125:400 mg/kg body weight), alloxangroup+henna extract and noni.........

Keyword: Lawsoniainermis Linn, Morindacitrifolia L., and antihyperglycemic

Abstract: NS1 protein fraction of hepatitis c virus polyprotein on ps-nvp-hdodaresin.The protein was grown in a stepwise method from the resin . High efficiency of the resin in protein synthesis was proved beyond doubt by the estimation of purity of peptide synthesised.