Abstract: Costus speciosus (Costaceae) commonly known as keukanda is a medicinal plant, used in Ayurveda for treating various diseases, one of which is diabetes mellitus. This work include study of Petroleum ether, Ethanol and Water (Aqueous) extract of powders of the fresh and dried leaves of Costus speciosus (CS) were organized and their blood glucose lowering effect compared by administrating them at the dose of 100 mg/kg and 200 mg/kg orally to diabetic rats. The ethanol powder extract of fresh leaves at a dose of 200 mg/kg body weight was found to significantly reduce fasting blood glucose, an effect comparable to that of glimepiride, a known synthetic drug. This extract was experienced for blood parameter study like SGOT, SGPT, Total cholesterol, Triglyceride, Total protein, Serum HDL cholesterol and alkaline phosphatase and also for glycosylated haemoglobion study. Thus the Costus speciosus an edible vegetable, appears to be a safe alternative to reducing blood glucose. The study was performing to explore antidiabetic potential as it is not reported earlier
Keywords: Costus speciosus, Diabetes, SGOT, SGPT, HDL
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