Series-1 (March-April 2019)March-April 2019 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Antimicrobial Activities of Some Plant Extracts against Some Fungal Pathogens |
| Country | : | Saudi Arabia |
| Authors | : | Madeha N. Alseeni || Enas M. Allheani || Safaa Y. Qusti || Najlaa Y. Qusti || Sulafah A. Alotaibi || Hawazin A. Alotaibi |
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: | 10.9790/3008-1402010110  |
Abstract: One of the major clinical problems is the resistance of fungal species towards most of the used antifungal agents. The search for new antifungal drug from plants helped to overcome this problem. This study evaluated the effects of some fruits extracts cited in the Holy Quran as antifungal agents. In this study, antifungal susceptibilities assessment of water and methanolic extracts of fruits extracts were done against Aspergillus niger, Aspergillus parasiticus, Fusarium oxysporum, and Alternaria alternate by well diffusion method. Microdilution susceptibility assay was used in order to determine the minimal inhibitory concentrations (MICs) of the plant extracts. Among the evaluated plants, methanolic extract was more effective than water extract. The inhibition zone.........
Key words: Antifungal activity; Plant extract; MIC, Garlic
[1]. Adnan, M., Gul, S., Batool, S., Fatima, B., Rehman, A., Yaqoob, S., … Aziz, M. A. (2017). A review on the ethnobotany, phytochemistry, pharmacology and nutritional composition of Cucurbita pepo L. The Journal of Phytopharmacology JPHYTO, 6(62), 133–139.
[2]. Ahmad, I., Owais, M., Shahid, M., & Aqil, F. (2010). Combating Fungal Infections: Problems and Remedy. Springer Science & Business Media. https://doi.org/10.1007/978-3-642-12173-9_13
[3]. Alam, E. A. (2014). Innovare Academic Sciences Volatile Components Of Banana Peels Tea ; A New Pharmaceutical Product, 6(3), 6–7.
[4]. Arif, T., Bhosale, J. D., Kumar, N., Mandal, T. K., Bendre, R. S., Lavekar, G. S., & Dabur, R. (2009). Natural products - Antifungal agents derived from plants. Journal of Asian Natural Products Research, 11(7), 621–638.
[5]. Ateeq, A., Sunil, S. D., Varun, S. K., & Santosh, M. K. (2013). Phoenix dactylifera Linn.(PIND KHARJURA): A review. International Journal of Research in Ayurveda and Pharmacy, 4(3), 447–451.
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| Paper Type | : | Research Paper |
| Title | : | Comparative Quality Assurance Assessment of some Commercially Available Brands of Paracetamol tablets in Benin City Metropolis, Edo State, Nigeria |
| Country | : | Nigeria |
| Authors | : | Obarisiagbon Aiwaguorejohnbull || Ovile Gift || Umoru Albert || Egbunu Hauwa Kulu |
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: | 10.9790/3008-1402011117 |
Abstract: Paracetamol (acetaminophen) is a drug used to temporarily relieve mild to moderate pain associated with headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and to reduce fever. It is one of the most found over the counter (OTC) drugs in many households and also the most perceived frequently faked product worldwide. This study was carried out to comparatively assess the quality of paracetamol tablet brands sold in the different pharmacies, dispensaries in Benin City metropolis with reference to Pharmacopoeia standards. Materials and method: A total of 11 brands of paracetamol conventional tablets(500mg) were purchased from different locations in Benin City. Quality control parameters like organoleptic, weight variation, hardness, friability, tensile strength, disintegration........
[1]. Dipak J. kanabar (2017). A clinical and safety review of paracetamol and ibuprofen in childen. Inflammopharmocology, 25(1): 1 – 9. doi: 10.1007/s 10 787-016-030 2-3
[2]. Maurizio de Martino and Alberto Chiarug (2015). Recent Advances in Pediatric use of Oral Paracetamol in Fever and Pain Management. Pain Ther. 4(2): 149 – 168. Dio: 10. 1007/s 40122 – 015 – 0040 Z.
[3]. What dose of paracetamol for older people? (2018). Drug and Therapeutics Bulletin, 56(6): 69 – 72.
[4]. Wiffen PJ, Derry S, Moore RA,McNicol ED, Bell RF, Carr DB, Mcintyre M and Wee B (2017).Oral paracetamol (acetaminophen) for cancer pain. Cochrane Database of Systemic Reviews. Issue 7. Art No: CD012637. Doi: 10. 1002/ 14651858. CD012637. Pub2
[5]. Chow S (1997). Pharmaceutical validation and process controls in drug development. Journal of Drug Information, vol. 31, pp 1195 – 1201.
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| Paper Type | : | Research Paper |
| Title | : | Characterisation of a Bacterium Lipase (Pseudomonas Fluoresens) From Vegetable Oil Polluted Soil |
| Country | : | Nigeria |
| Authors | : | Popoola, B.M || Onilude, A.A, || Fakayode I.B |
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: | 10.9790/3008-1402011826 |
Abstract: Bacteria are very useful in protecting the environment. The lipolytic activities of physiologically diverse bacteria have great potential to degrade oil spills in the environment. There is need for extensive characterisation of the bacterium lipase for the treatment of vegetable oil-polluted sites. This work was carried out to preliminarily characterise the lipase of Pseudomonas fluoresens. Pseudomonas fluoresens was screened for lipase production using standard methods. Temperature, pH, ion concentration (NaNO3 and MgSO4), enzyme concentration, nitrogen concentration, substrate concentration, time course and agitation speed were optimised for the lipase activity as well as growth. Crude enzyme of Pseudomonas fluoresens had.......
Key words: Vegetable oil spill, Lipase production, characterisation
[1]. Arpigny, J.L and Jaeger, K. 1999. Bacteria lipolytic enzyme: Classification and properties. Biochemical Journal 343(1): 177-183.
[2]. Becker, P., Koster, D., Popov, M.N., Marboss Ian, S., Antrtanikian, G. and Markl, H. 1999. The biodegradation of olive oil and treatment of lipid rich wool, waste. Water under aerobic thermophilic condition. Water Resources. 133: 653-660.
[3]. Benjamin, S. and Pandey, A 1997. Coconut cake: A potent substitute for production of lipase by Candida rugosa in solid state fermentation. Acta Biotechnology. 17: 241-251.
[4]. Benjamin, S. and Pandey, A 1998. Candida rugosa lipases: Molecular biology and versatility in biotechnology. 14(12): 1069-1087.
[5]. Bradoo, S., Saxena, R.K., Gupta, R., 1999.Partitioning and resolution of mixture of two lipases from Bacillus stearothermophilus SB1 in aqueous two-phase system.ProcessBiochemistry.35: 57– 62..
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| Paper Type | : | Research Paper |
| Title | : | Isolation and identification of Lactobacillus plantarum KM5 from camel milk for β-galactosidase production |
| Country | : | Egypt |
| Authors | : | Khadra Al-Zahrani || Reda Allam || Reda Amasha || Samyah Jastaniah || Magda Aly |
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: | 10.9790/3008-1402012735 |
Abstract: βgalactosidase is a magic and promising enzyme, usually produced frommicroorganisms, plantsand animals for different applications like preparation of lactose-free milk for food and dairy products. It was used for hydrolysis of the glucosidic bond of lactose and produced glucose and galactose. Lactose is the main sugar which was found mainly in milk and whey. Bacteria are usually used as a source of the active enzyme. In this research,twenty lactic acid bacterial isolates were obtained from dairy product samples which were collected from Jeddah, Saudi Arabia. All the bacterial isolates were screened for the presence of β-galactosidase on MRS agar medium. Only seven bacterial isolates showed green colons on MRS (Mann, Rogosa and Sharp) agar medium containing X –gal.The amount of β-galactosidase was determined by spectrophotometer using oNPG as substrate. The highest β-galactosidase producer was the isolates KM5 and W1. Comparing the two isolates deeply, isolate KM5 was the best and.......
Key words: β-galactosidase, Lactic acid bacteria, MRS agar medium, X –gal, Lacobacillus acidophilus
[1]. Akolkar, S.K.; Sajgure, A. and Lele, S.S. (2005). Lactase Production from Lactobacillus acidophilus. World Journal of Microbiology and Biotechnology, 21 :( 6-7): 1119-1122.
[2]. Anumukonda, P. and Tadimalla, P. (2010). Optimization of bioprocess parameters for the production of β-galactosidase by employing statistical methods.International Journal of Pharma and BioSciences, 1(3): 11-17.
[3]. Assefa, E.; Beyene, F. and Santhanam, A. (2008).Isolation and characterization of inhibitory substance producing lactic acid bacteria from Ergo, Ethiopian traditional fermented milk. Livestock Research for Rural Development, 20 (3):1-6.
[4]. Banerjee G, Ray A and Hasa K N (2018). Is divalent magnesium cation the best cofactor for bacterial β-galactosidase?. J.Biosci., Vol. 43, No. 5, pp. 941–945
[5]. Bury, D.; Jelen, P. and Kaláb, M. (2001). Disruption of Lactobacillus delbrueckii ssp. bulgaricus 11842 cells for lactose hydrolysis in dairy products: a comparison of sonication, high-pressure homogenization and bead milling. In novative Food Science and Emerging Technologies., 2 :( 1): 23–29..