Version-1 (Nov-Dec 2018)
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Abstract: The two natriuretic peptides, A-type Natriuretic peptide (ANP), B type Natriuretic peptide (BNP) are released by the heart while C-type natriuretic peptide (CNP) is mostly expressed in the brain but also by the endothelial cells and heart and they induce natriuresis and have vasodilatory actions. On the other hand, aldosterone released by the adrenal cortex may regulate the release of natriuretic peptides by acting on specific receptors in the heart and increasing the circulating sodium and ECF levels. This article examines the mutually homeostatic regulatory role of natriuretic peptides and aldosterone in maintaining cardiovascular system and other possible biological roles. This may be more relevant in cardiovascular disorders like hypertension and cardiac failure...
Key words: ANP, BNP, CNP, Aldosterone, heart, expression, receptor
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Abstract: Objective: To estimate the usefulness of the Indian diabetes risk score for detecting undiagnosed diabetes in the rural area of Bhadradri Kothagudeam ,Telangana. Materials and Methods: The present study was conducted in the field practice area of The Sigareni Collieries Company Ltd Main Hospital, Kothagudem,Telangana, covering a population of 300 from Dec 2017 to May 2018 by using a predesigned and pretested protocol to find out the prevalence and the risk of diabetes mellitus in general population by using Indian diabetes risk score tool. Results: 300 respondents comprising 152 (50.66%) females and 148 (49.39%) males were studied. Most of the respondents 202(67%) indulged in mild to moderate physical activity. 149(49.64%) individuals were in the overweight category (>25BMI). Out of these overweight persons, 25% had high diabetic risk score. It is observed.........
Key words: Diabetes mellitus, Indian diabetes risk score, rural area, risk factors, obesity
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Abstract: Antimicrobial resistance is an issue of great significance for public health at global level. The purpose of study is to determine the susceptibility patterns of microrganisms to antibiotics and the prevalence of antibiotic resistance among common pathogens in a tertiary care teaching hospital. The study was conducted in a 1000 bedded multispecialty hospital in South India. The study was carried out in three phases as retrospective, prospective and comparative study. The major organism isolated was Klebsiella followed by Staphylococcus. E.coli and Klebsiella were found to be more sensitive to Amikacin. Specimen in which Klebsiella, Pseudomonas and Streptococcus were found to be more was in sputum. E.coli and Proteus were present more in urine. Staphylococcus........
Key words: Bacteria,Antimicrobial susceptibility,Resistance
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Abstract: Objective: Rose is the most popular cut-flower world-wide and in Kenya it accounts for about 38 % in floriculture value chain. However, its production faces significant challenges due to pests and diseases. In particular, crown gall disease caused by Agrobacterium tumefaciens is one of its most limiting factors of production. The disease causes substantial yield loss which warrants an urgent need to explore sustainable management options. The management of crown gall in roses currently includes cultural practices and chemical control methods. The study aimed at evaluating the antagonistic activity of naturally occurring Agrobacterium radiobacter isolates from different flower farms in Nanyuki, Naivasha, Murang'a and Timau against Agrobacterium tumefaciens. In addition, Elianto oil, copper hydroxide (kocide 2000) and copper oxychloride were evaluated as chemical control agents.....
Key Words: Rose plants, antagonism, copper kocide, copper oxychloride, Elianto oil, Agrobacterium tumefaciens, Agrobacterium radiobacter
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Abstract: Trypanosomiasis is a parasitic disease that affects both humans and animals. It is caused by the parasitic protozoan, trypanosome,. The development of a vaccine for the treatment of the disease is becoming increasingly complicated due to the problem of antigenic variation, thus the reliance on chemotherapeutic agents to control the disease.Drugs derived from natural sources play an important role in the avoidance and treatment of human diseases.Recent studies have shown a variety of health properties of endophytic fungal extract. The ethylaceted and the methanolic extraction were carried out. The bioactive fungal extract was tested invitro on Trypanosoma brucei brucei (federe strain). The in vitro assessment of Acremonium sp extract show graded trypanocidal activity at different concentrations with LC50of0.204, as indicated in the table of percentile. It also shows that as the concentration Increase the mortality also increases.
Key wordsTrypanosome Endophytic Brucei Acremonium.
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