Abstract:2-(2-Chlorophenyl)-1H-benzo[d]imidazolederivatives were prepared by condensing2-(2-Chlorophenyl)-1H-benzo[d]imidazole with different heterocycles.The synthesized derivatives were characterized by IR,1H NMR,13C NMR,massand elemental analysis. The compounds were screened for in vitro and microbial activity against panel of selected gram positive and gram negative bacterial strains using Ciprofloxacin as standard and molecular docking done with a Biotin carboxylase from E. Coli PDB CODE(3JZI).
Keywords: 2-(2-Chlorophenyl)-1H-benzo[d]imidazole; Antimicrobial agents;ciprofloxacin:Molecular docking:
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