Volume-18 ~ Issue-4 ~ April 2025

Abstract: The simple and sensitive spectrophotometric method for the determination of Torsimide reacts with 1ml of DDQ (2, 3 –dichloro -5, 6-dicylano-1, 4-benzoquinone) by charge –transfer complex method. In this method the drug Torsimide as n-electron donors with acceptor 2, 3 dichloro-5, 6- dicyano 1,4- benzoquinone (DDQ) to form Dark red color charge-transfer complexes. This reaction is instantaneous and quantitative. The drug maximum absorbance at 460 nm and......

Keywords: Torsimide, DDQ, chloroform, methanol, UV Spectrophotometric Method

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Abstract: The multicomponent reactions of aniline, aldehydes and 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one in ecofriendly deep eutectic solvent were developed. The Choline chloride based deep eutectic solvent played a dual role as a solvent as well as catalyst and produced excellent yield of 1H-pyrazolo[3,4-b]quinolines under mild reaction conditions. It could be recycled for several runs without any loss of catalytic efficiency. This methodology offers several advantages like simple and straightforward synthesis, shorter reaction time, environmental sustainability and use of natural resources.

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Abstract: Quantitative structure-activity relationship (QSAR) is a statistical modelling approach mostly used in molecular modelling, property and activity prediction of new molecule, drug discovery and prediction of environment. QSAR studies have been performed on 17 molecules of phenol and its derivatives. These quantitative structure-activity relationship models are based on few calculated and experimentally obtained Biological Activities Half Maximal Inhibitory concentration (IC50)......

Keywords: IC50, QSAR, Molecular descriptors, 3D MoRSE descriptors, FDI descriptors, RDF descriptors, Moreau autocorrelation descriptors, correlation coefficient, PRESS, SPRESS, PSE, LSE, PE.

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Abstract: Fatty acids are essential for the structure and function of biological systems, and they are the primary source of energy. Avocado oil has high levels of omega-6 and omega-9 fatty acids, as well as natural antioxidants, which help lower total cholesterol, triacylglycerol, and low-density lipoprotein (LDL) cholesterol while maintaining healthy high-density lipoprotein (HDL) cholesterol levels. Avocado's fatty acid profile varies depending on cultivar, plant portion, ripening stage, geographical location, and sampling procedures. The purpose of this study was to......

Keywords: Avocado; Fatty acid; Cultivars, Altitude

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Abstract: Background: Water contamination is a major global issue that necessitates the development of new and sustainable purification technologies. Aerogels, ultra-light porous materials with a large surface area and unique properties, have emerged as promising candidates for water treatment, particularly in removing organic contaminants. These materials are highly porous and low-density foams with a microstructure consisting of nano-sized pores and interconnected primary particles......

Key Word: Persistent; Organic; Pollutants; Aerogel; Sol-gel; Oxidation; Activated; Carbon

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