Volume-6 ~ Issue-3
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Objective: To study the prevalence of anemia and socio-demographic factors associated with anemia among pregnant women attending antenatal hospital. Material and methods: Total 100 pregnant women were selected for the study and the study was carried out from Sep 2011 to Jan 2012. Pretested and prestructured questionnaire was used to collect general information. Blood samples were collected by qualified technician for hemoglobin estimation. Socio-economic classification by B.G. Prasad was adopted. Classification of anemia by WHO was used. Chi-square test was used for statistical analysis. Results: Overall prevalence of anemia among the pregnant women was found to be 63%. Factors such as level of education and socio-economic status were found to be significantly associated with prevalence of anemia. Conclusion: There is a need for realization that health system should focus on various factors that contribute to the occurrence of anemia and include them as important mediators in the National Health Policy.
Key words: - Anemia, Socio-economic classification, Hemoglobin.
[1]. World Health Organization, Technical Report series; 1968.
[2]. Dr. Madhu Ahuja, Senior Consultant; Max Health Care, Caring for you for life; A max Indian Institution , 2002 , Anemia in pregnancy.
[3]. Tinker A. Women's health : The unfinished agenda. Int J. Gynecology obstet 2000 ; 70 : 14 9 - 158 .
[4]. US Department of Health and Human services women and smoking : a report of surgeon general. Rochville, MD : US Department of Health and Human Services, Public Health Service, Office of the Surgeon General, 2001.
[5]. Tolentino K, Friedman JF. An Update on Anaemia in less developed countries. Am J Trop Med Hygiene & 2007; 77(1) : 44-51.
[6]. Toteja GS, Singh P., Dhillon BS et al. Prevalence of anemia among pregnant women and adolescent girls in 16 distrcts of India. Food and Nutrition Bulletin 2006; 27(4) : 311-315.
[7]. Prema Rama Chandran Nutrition in Pregnancy. Women and Nutrition in India, Nutrition Foundation of India (1989) 153-193.
[8]. Saleem S, McClure EM. Pregnancy behaviour of Pakistani Women over their Reproductive life span. Al Ameen J Med Sci 2010; 3 : 228-236.
[9]. Shen and Wei. Adverse Maternal Outcomes for Women with Different Health Insurance Status in Nevada. J Nevada Public Health Assoc 2008; 5.
[10]. AK Agarwal. Social Classification : The need to update in the present scenario. Indian Journal of Community Medicine. Vol. 33, No. 1, January 2008.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Malaria infections in a stable endemic malaria community of Abagana, a rainforest community in southeastern Nigeria was studied between April and August 2012. Advocacy visits to the traditional ruler and opinion leaders of the community and proper explanations of the project were used to obtain permission to carry out the study. The community was mobilized through public announcements in the churches, schools, markets and group meetings. Thick and thin blood films were used to concentrate, and identify malaria parasites using oil immersion lense of bright field light microscope. Estimates of parasite intensity per person was made on each positive slide by parasite count in the microscope fields. Participants were grouped into sexes, age, education and occupation. A total of 141 participants made up of 59(41.84%) males and 82(58.16%) females were involved in the study. Of the 141 participants, 76(53.90%) were positive with malaria parasites, among whom 32(42.11%) were males and 44(57.89%) were females. Of the positive malaria cases, malaria intensity among the participants were light 32(42.11%), moderate 35(46.05%) and heavy 9(11.84%) and was spread across all the groups and villages. These results revealed holoendemicity of malaria in the community. Intervention efforts including massive educational campaigns were suggested.
Keywords- Endemic,holoendemicity,intensity,parasite,rainforest
[1] D. Warrell, Pathophysiology of severe falciparum malaria in man. Symposia of the British Society of Parasitology, Parasitology. 24(94),1987, S53-S76.
[2] J. Sahr, Malaria and its effect on vertebrate host. J. Clin. Med., (21), 2000, 97-202.
[3] A.V. Kondrachine, and P.T.Trigg , The current global malaria situation 11-12 in Sherman ed. Malaria parasite biology, pathogenesis and protection. ASM press. (Washington DC, 1997) 123-126.
[4] WHO, Making every mother and child count. World Health Organization, Geneva. The World Health Report., 2005a.
[5] I. Sherman, A brief history of malaria and discovery of the parasite lifecycle. In malaria parasite biology, pathogenesis and protection. Sherman I.W.ed. (ASM press, Washington DC. 1998) 347-353.
[6] Roll Back Malaria, Facts about malaria in Nigeria,Abuja.Publication on the Roll Back Malaria, 2005, 1-2.
[7] Federal Ministry of health, National Treatment Guidelines Federal Ministry of Health. Publication of the FMH, Nigeria, 2005a, 44. [8] F. Ukoli, The Biology and natural history of malaria. Proceedings of the annual convention and scientific assembly. Archives of Ibadan medicine 1(2), 2003, 35-36.
[9.] K. Abdullahi., U. Abubakar., and T. Adamu, Malaria in Sokoto,North western Nigeria., African Journal of Biotechnology, 8(24), 2009, 7101-7105.
[10] B. Uzochukwu, and O. Onwujekwe, Socio-economic differences and health seeking behaviour for the diagnosis and treatment of malaria: a case study of four local government areas operating the Bamako initiative programme in south- east Nigeria., International Journal for Equity in Health, 2001.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: Photochemical crosslinking is a best alternative method when compared to conventional crosslinking methods such as chemical and physical methods, by using vitamins like riboflavin and ascorbic acid as photochemical initiators to enhance the physicochemical properties of collagen poly (vinyl pyrrolidone) blend without any toxic by products. Collagen and poly (vinyl pyrrolidone) blends were investigated by Fourier transform infrared spectroscopy (FTIR), Differential scanning calorimetry (DSC), Swelling studies, Tensile testing and the surface properties were studied by Contact angle measurements and Microscopy. Collagen and PVP blended samples were irradiated with the UV light wavelength λ=300nm for 30 minutes by using 0.03% riboflavin and ascorbic acid as photosensitizers and the samples were air dried at room temperature. Collagen- PVP blended hydrogels showed good swelling properties and the lower contact angles indicate their hydrophilic nature. The photochemical crosslinking also improved the thermal stability of the hydrogels which can be confirmed by broad endothermic peak between 80-1800C in the thermoscan. The FTIR spectral changes clearly exhibited that these two polymers were strongly crosslinked and miscible.
Keywords - Collagen, Poly (vinyl pyrrolidone), Photochemical crosslinking, Vitamins, Hydrogel, Drug delivery
1]. K.T. Nguyen, J.L. West, Photopolymerizable hydrogels for tissue engineering applications, Journal of Biomaterials.2002;23:4307–4314.
[2]. W.E. Hennink, C.F. van Nostrum, Novel cross linking methods to design hydrogels, Journal of Advanced Drug Delivery Reviews, 54, 2002, 13–36.
[3]. M. Ahearne, Y. Yang, K. Y. Then and K. K Liu, Non-destructive mechanical characterisation of UVA/riboflavin crosslinked collagen hydrogels, Journal of Ophthalmology,.92, 2002, 268-271.
[4]. K. Fujioka, M. Maeda, T. Hojo, A. Sano, Protein release from collagen matrices. Advanced Drug Delivery Reviews, 31, 1998, 247-266.
[5]. N. Nishad Fathima, M. Chandra Bose, J. Raghava Rao , U.N. Balachandran , Stabilization of type I collagen against collagenases (type I) and thermal degradation using iron complex. Journal of Inorganic Biochemistry, 100, 2006, 1774–1780.
[6]. A. Sionkowska, J. Kozlowska, A. Planecka, J. Skopinska-Wisniewska, Photochemical stability of poly(vinyl pyrrolidone) in the presence of collagen Polymer Degradation and Stability, 93 , 2008, 2127–2132.
[7]. S. Benamer, M. Mahlous, A. Boukrif, B. Mansouri, S. Larbi Youcef, Synthesis and characterisation of hydrogels based on poly(vinyl pyrrolidone). Nuclear Instruments and. Methods in Physics Research B 248, 2006, 284–290.
[8]. H. Kaplan , A. Guner, Characterization and determination of swelling and diffusion characteristics of poly(N-vinyl-2-pyrrolidone) hydrogels in water, Journal of Applied Polymer Science 78, 2000, 994-999.
[9]. K.P. Rao, K.T. Joseph, CRC Press, Collagen graft copolymers and their biomedical applications, in: M.E. Niimi (Ed.), Collagen Volume III Biotechnology, Boca Raton, FL. 1988; 63–86.
[10]. A. Sionkowska, Interaction of collagen and poly vinyl pyrrolidone in blends, European polymer Journal, 39, 2003,2135-2140.
- Citation
- Abstract
- Reference
- Full PDF
Abstract: The current orthodox treatment modalities for diabetic mellitus have many setbacks including undesirable side effects and the high cost of long term treatment. The aim of this study was to determine the anti-diabetic effectsand compare some biochemical parameters of four plants; Ocimumgratissimum (OG),Aloe vera (AV), Brassica oleracea(BO) and Ipomoea batatas(IB) on alloxan induced diabetic rats. The preliminary phytochemical screening reveals the presence ofalkaloid, tannin, cardiac glycoside, resin and steroids in all four plants. Diabetic was induced by interperitonial injection of alloxan monohydrate while treatment was done for 21 days. Diabetic rats had significant increased (P˂0.05)cholesterol, triglyceride (TG), Low Density Lipoprotein (LDL) and artherogenic index (AI). Treatment of experimental rats with 150 mg/kg bw. of aqueous extractsof plants significantly decrease (P˂0.05) the levels of cholesterol and LDL in OG and BO treated groups when compare with the control. Computed artherogenic index was significantly reduced (P˂0.05) in AV treated group when compared to the control. Aqueous extracts also significantly (P˂0.05) alter serum concentrations of alkaline phosphatase (ALP), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in a similar manner with metformin treated group. Result showed that decrease in plasma glucose was in the order IB˃OG˃BO˃AV. All plant extracts possess antidiabetic, anti-hyperlipidemic effects and were able to ameliorate the weight loss observed in diabetic rats. Keywords: Aloe vera,Brassicaoleracea,Comparativestudies,Diabetics,Ipomoeabatatas,Ocimumgratissimum
[1] J. Owolabi,E.K.I. Omogbai,andO. Obasuyi, Antifungal and antibacterial activities of the ethanolic and aqueous extract of Kigeliaafricana (Bignoniaceae) stem bark, Afr. J. Biotechnol,6 (14), 2007, 882-85.
[2] P. E. Albert and V. Francis,African Natural Plant Products; New Discoveries and Challenges in Chemistry and Quality, 7, 2009, 135-147.
[3] G.B. Kavishankar, V. Lakshmidevi, M.N. Mahadeva,H.S.Prakash,S.R. Niranjana,Diabetes and medicinal plants-A review, Int J Pharm Biomed ScI,2(3), 2011, 65-80.
[4] K.D. Effraim, T.W. Jacks., O.A. Sodipo,Histopathological studies on the toxicity of Ocimumgratissimumleave extract on some organs of rabbit,Afr J Biomed Res, 6, 2003, 21-5.
[5] K.S. Prabhu, R. Lobo, A.A. Shirwaikar, and A.Shirwaikar, Ocimumgratissimum: A Review of its Chemical, Pharmacological and EthnomedicinalProperties,The Open Complementary Medicine Journal,1, 2009,1-15.
[6] A. Mohammed, Y. Tanko, M. A. Okasha,R.A.Magaji, and A.H. Yaro,Effects of aqueous leaves extract of Ocimumgratissimumon blood glucose levels of streptozotocin induced diabetic wistarrats,Afr J Biotechnol, 6, 2007, 2087-90.
[7] A.A. Oryan, A.T. Naeini, B. Nikahval, and E. Gorjian, Effect of aquoues extract of Aloe vera on experimental cutaneous wound healing in rats, Vet. Arhiv,80, 2010, 509 – 522.
[8] A. Noor, S. Gunasekaran, A. Manickam, and M. Vijayalakshmi.Antidiabetic activity of Aloe veraand histology of organs in streptozotocininduced diabetic rats,Curr. Sci., 94, 2008, 1070-1076.
[9] M.F. Ahmed, A. Srinivasa,S.R.Ahemad, and M. Ibrahim,Protective Effect of Brassica oleracea L. var. capitataagainst Simvastatin Induced Hepatotoxicity in Rats,Int. Res. J. of Pharmaceuticals, 02(04), 2012, 91-97.
[10] F. Hayase, and H. Kato,Antioxidative components of sweet potatoes, J. Nutritional Science and Vitaminology, 30, 1984, 37-46.
