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Abstract: Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for liver injury. The present study was conducted to evaluate the hepatoprotective activity of methanolic extract of whole plant of Pulicaria wightiana in wistar rats. The studies were conducted using the two popular inducing agents Paracetamol (2 g/kg, p.o.) in 1% NaCMC and Carbon tetrachloride (1 ml/kg). Silymarin (100 mg/kg, p.o.) was used as reference drug in the respective models. The effect was estimated by measuring the enzymatic levels and histo- pathological studies..............
Keywords: Carbon tetrachloride, flavanoids, hepatoprotective, paracetamol, Pulicaria wightiana.
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Abstract: Background and objective: Recent research has elucidated a close association between intestinal microbiota, obesity, insulin resistance and nonalcoholic hepatic injury. Various studies have also indicated an increase in hepatic marker enzymes in obesity. Hence, this study aims to evaluate the association of gut microbiota with obesity, insulin resistance and hepatic marker enzymes. Material and Method: This case-control study was conducted during March 2015 to October 2016 At S.C.B Medical College, Cuttack, Odisha. The study included 186 subjects (86 irritable bowel syndrome patients as per the Rome III criteria and hundred matched controls). Plasma fasting glucose, serum lipid profile, hepatic marker enzymes were analysed by commercial kits adapted to automated clinical chemistry analyser and serum fasting insulin was estimated by kits adapted to Lisa Scan................
Keywords: Irritable bowel syndrome, liver enzymes, obesity, nonalcoholic liver disease
[1]. Caricilli AM, Saad MJ. The role of gut microbiota on insulin resistance. Nutrients 2013;5:829-51.
[2]. D'Aversa F, Tortora A, Ianiro G, Ponziani FR, Annicchiarico BE, Gasbarrini A. Gut microbiota and metabolic syndrome. Intern Emerg Med 2013;8 Suppl 1:S11-5.
[3]. Le Roy T, Llopis M, Lepage P, Bruneau A, Rabot S, Bevilacqua C, et al. Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice. Gut 2013;62:1787-94.
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Abstract: In Nigeria, malaria consistently ranks among the five most common cause of death in children. This study investigated the prevalence of malaria and socioeconomic status of someresidents of Emohua Community, Rivers State, Nigeria.Following ethical clearance which was obtained from the University of Port Harcourt and the parents of the subjects who gave their written consents, blood samples were collected through vein puncture from 200 subjects within the age 0-17years, from July 2014-February 2015. Structured questionnaire were administered to the subjects and parents provided answers for younger children.Thick and Thin films were examined microscopically using oil immersion objective following the standardparasitological method............
Keywords: Malaria parasitaemia, Socio-economic status, Emohua community, Rivers State, Nigeria.
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Abstract: The present study was conducted in Diyala province for the period from15/ 1 / 2016 to 15 / 12/ 2016, In the Central Blood Bank in the public Health Laboratory in Diyala. The aim of the study was to detection the rate of Occult Hepatitis B virus infection among blood donors using ELISA test to screening different serological markers (HBs Ag, anti- HBs and anti- HBc IgM). The study included; 200 apparently healthy blood donors were attended central blood bank in Diyala. 183of blood donors were males and 17 were females. The age range was 18 years to 58 years............
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[5]. Amadin, A.O.; Adesola, O. O.; Lateef, S. and et al. (2016). Occult Hepatitis B virus infection in previously screened, blood donors in Ile-Ife, Nigeria: implications for blood transfusion and stem cell transplantation. Virology Journal. 13: 76.
