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| Paper Type | : | Research Paper |
| Title | : | Identification of lead compounds against human hepatitis B viral capsid protein in three medicinal plants through in silico method |
| Country | : | India |
| Authors | : | Subin Mathew M S || Sreekumar S || Biju C K |
Abstract: Hepatitis B viral infection is a serious health problem in all over the world and its treatment is expensive with limited success (30-40%.) The current treatment system may induce serious side effects. It is well acknowledged that plant-derived drug molecules are safe and cost effective. In traditional medicine, several plants have been used as hepatoprotective but its efficacy and mode of molecular mechanism of drug action are seldom investigated.......
Keywords: AutoDock, Allamanda cathartica, Docking, Hepatitis B, Phytochemicals, Solanum indicum, Vigna mungo,
[1]. WHO report, July 2015 http://www.who.int/mediacentre/factsheets/fs204/en/
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[3]. T. J. Liang, Hepatitis B: The virus and disease, Hepatology, 49(5),2009, S13-S21.
[4]. M. Arooj, M. Sattar, M. Safdar, S. Kalsoom, and S Shahzad, In silico molecular docking and design of anti-hepatitis B drugs, IOSR Journal of Pharmacy and Biological Sciences, 3(6), 2012, 41-55.
[5]. V. Prabhadevi, S. S. Sathish, M. Johnson, B. Venkatramani, and N Janakiraman, Phytochemical studies on Allamanda cathartica L. using GC-MS, Asian Pacific Journal of Tropical Biomedicine, 1, 2012, S550-S554.
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| Paper Type | : | Research Paper |
| Title | : | Mineral Responses of P. Vulgaris L. To Telfairia Mosaic Virus Infection |
| Country | : | Nigeria |
| Authors | : | Mofunanya, A. A. J. |
Abstract: Mineral responses of P. vulgaris to Telfairia mosaic virus (TeMV) infection were investigated. Saponins, alkaloids, tannins and reducing sugars showed significant (P< 0.05) reductions in response to TeMV infection with percentage reductions of 89.3%, 54.5%, 46.3% and 18.3% respectively. Protein showed insignificant increase of 4.3% in inoculated samples.......
Keywords: Mineral responses, Phaseolus vulgaris, Telfairia mosaic virus infection.
[1]. Ecocrop 2013. Ecocrop database. FAO, Rome Italy.
[2]. S. Smoliak, R. L. Dittterline, J. D. Scheetz, L. K. Holzworth, J. R. Sims, J. R. Wiesner, D. E. Baldridge, G. L. Jibke, Common bean. Montana State University, Animal and Range Sciences Extension Service, Forage Extension Program. (Zozeman: USA,1990).
[3]. T. Sandra, J. Trupti, B. Kimberly, B. Campbell, X. U. Scheffler. Dong, C. Bret, T. N. Henry, and T. Gary General ton of Phaseolus vulgaris ESTS and investigation of their regulation upon uromyces appendiculatus infection. BCM Plant Biology. 9, 2009, 46.
[4]. C. S. Wortmann, Phaseolus vulgaris L. (Common bean). in Brink, M and Belay, G. (Ed.) Record from prota4U.prota (Plant resources of tropical Africa/ ressources vegetales de I'Afrique tropicale), (Wageningen, Netherlands, 2006).
[5]. Ecoport, 2013. Ecoport database. Ecoport. FAO, Rome Italy.
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| Paper Type | : | Research Paper |
| Title | : | Coenzyme Q10 - A Review of Its Promise |
| Country | : | India |
| Authors | : | S. Arshiya Banu || S. Asadulla || M. Venkata Subbaiah |
Abstract: Coenzyme Q10 (CoQ10) is a powerful antioxidant found in the membranes of many organelles. Experimental studies in animal models suggest that CoQ10 may protect against neuronal damage that is caused by ischemia, atherosclerosis and toxic injury. It buffers the potential adverse consequences of free radicals produced during oxidative phosphorylation in the inner mitochondrial membrane........
Keywords: Coenzyme Q10, antioxidant, statins, cardiovascular diseases, neurodegenerative disorders, diabetes, cancer.
[1]. Ernster, L; Dallner, G (1995). "Biochemical, physiological and medical aspects of ubiquinone function". Biochimica et Biophysica Acta 1271 (1): 195–204. doi:10.1016/0925-4439(95)00028-3. PMID 7599208.
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| Paper Type | : | Research Paper |
| Title | : | Comparative Acute Toxicity Studies of Selected Indigenous Herbal Plants in Swiss Albino Mice |
| Country | : | India |
| Authors | : | Ram Garg || Rahul Kumar || Deepak Nathiya || Omprakash Goshain || Vinita Trivedi || Ashish Kumar Sharma || Krishna Murti |
Abstract: Objective: Toxicology may be defined as the study of harmful / poisonous effects of drugs and other chemicals with emphasis on detection, prevention and treatment of poisonings. The present study was aimed to determine LD50 and to establish the safety margin ofdifferent solvent extracts of selected herbal plants sources namelySaussurea lappa (Root), Ficus bengallensis (Root ), Flacourtria romantchi (stem bark and Root), andOroxyllum indicum (Root ) by acute toxicity study in Swiss albino mice as per OECD guideline 425........
Keywords: Acute toxicity(LD50), Root extract of Saussurea lappa(RESL), Root extract of Ficus bengallensis (REFB), Stem bark and root extract of Flacourtria romantchi(SBAREFR), root extract of Oroxyllum indicum (REOI), OECD guideline 425.
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