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| Paper Type | : | Research Paper |
| Title | : | Study of Bacterial Isolates and their Susceptibility Pattern in Chronic Suppurative Otitis Media |
| Country | : | Iraq |
| Authors | : | Zina Bakir Al-Hilli |
Abstract: Chronic Suppurative Otitis Media (CSOM) is one of the common ear diseases which can cause many complications if not treated properly . This study was done to determine isolates causing CSOM and their antibiotic susceptibility pattern. The study was carried out from November 2014 to April 2015. Ear swabs were collected & cultured from one hundred and twenty patients with CSOM attending the ENT Out Patient Clinic in Al- Hillah Teaching hospital. The specimens were cultured The isolated organisms were identified by standard microbiological methods.
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[2]. Maharjan, M.; Bhandari, S.; Singh, I.; and Mishra, S. C. (2006). Prevalence of otitis media in school-going children in eastern
Nepal. Kathmandu Univ. Med. J.16:479-82.
[3]. Berman, S. (1997). Classification and criteria of Otitis Media. Clin. Microbiol. Infect. (Suppl). 3: 1-4.
[4]. Acuin, J.( 2004). Global burden of disease due to Chronic Suppurative Otitis Media: Disease, deafness, deaths and DALYs
Chronic Suppurative Otitis Media-Burden of Illness and Management Options.
[5]. Mirza, I. A.; Ali, L.; Ali, L. and Arshad, M. (2008). Microbiology of chronic suppurative otitis media - experience at Bahawalpur.
Pak. Armed Forces Med. J. 58:372-6.
[6]. Kena, M. (1988). Etiology and pathogenesis of chronic supporative otitis media. Arch. Otolaryngol. Head and Neck Surg. 97 (2)
(Suppl. 137): 16-17.
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| Paper Type | : | Research Paper |
| Title | : | The Central and Peripheral effects of the methanol extract of Fadogia cienkowskii schweinf. var cienkowskii Leaves |
| Country | : | Nigeria |
| Authors | : | Ode O.J. || Omeje J.N. || Nuhu U. || Oladele G.M. || Madubuike S.A. |
Abstract: The methanol extract of Fadogia cienkowskii schweinf. var cienkowski leaves was investigated for central and peripherally mediated nervous effects. Oral acute toxicity studies, the effect on phenobarbitone-induced sleeping time, local anaesthetic effects, analgesic activity using acetic acid-induced writhing response, and muscle relaxant effects with hind limb grip reflex and inclined board tests were carried out on the methanol extract following standard models. The extract was tolerated by the oral route up to the highest test dose of 4000 mg/kg; hence, there was no mortality or overt clinical manifestations in mice within 48 h duration of the investigation.
[1]. J.M. Kong, N.K. Goh, L.S. Chia, and T.F. Chia, Recent advances in traditional plant drugs and orchids, Acta Pharmacology Science, 24, 2008,7-21.
[2]. H.P. Rang, M.M. Dale, J.M. Ritter, and P.K. Moore, Pharmacology (London: Churchil Livingstone, 2003) 503-514.
[3]. J.B. Calixto, A. Beirith, J. Ferreira, A.R.S. Santos, V.C. Filho, and R.A.Yunes, Naturally occurring antinociceptive substances from plants, Phytother. Res., 14, 2000, 401-118.
[4]. J.D. Griffiths, N.V. Le, S. Grant, A. Bjorksten, P. Hebbard, and C.Royse, Symptomatic local anaesthetic toxicity and plasma ropivacaine concentrations after tranversus abdominis plane block for caesarean section, British Journal of Anaesthesia, 110, 2012, 996-1000.
[5]. G.B. Marino-Betlolo, Traditional medicine and health practice. J. Ethnopharmacol, 2, 1980, 5-7.
[6]. P.S.A. Emeline, C. A. Aristide, and S. Brice, Magnoliophyta, Biosphere Reserve of Pendjari, Atakora Province, Benin. Checklist, 8, 2012, 642-661.
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| Paper Type | : | Research Paper |
| Title | : | Effect of Indian Spices to Manage the Diabetes and Associated Metabolic Disorder |
| Country | : | India |
| Authors | : | Dinesh K. Garg || Pranav Pandya |
Abstract: India is a country, where we have more than four crores of insulin dependent diabetics and this number is growing regularly. The situation is more or less same in other developing/non developing neighboring countries and across the globe. This disease is a non-curable and the management is the only remedy using variety of systemic chemicals as drugs/insulin. The resistance to the drugs/insulin is also a challenge to strengthen the management for a longer period.
[1]. Ling Chew Yik.,Wan Chan Elaine, Tan Pei Ling, Linn Yau Yan, Stanlas Johnson, Kheng Goh Joo. Assessment of phytochemical content, poly phenolic composition, antioxidant and anti-bacterial activities of leguminosae medicinal plant in penninsular Malaysia, BMC complement Altern. Med. 11, 2011,12.
[2]. S M Karandikar, V A Pandit & S D Kulkarni, Pharmaco-epidermiological study of use of herbal medicine in elderly Pune, Bharati vidyapeeth Bull. 1 , 1997,9.
[3]. A K Gupta, N Tondon,"Review on the Indian medicinal plant" Indian Council of Medicinal Research, New Delhi. 2004,312
[4]. A Subramaniam. The problems and prospects of plant drug research in India: Pharmacological evaluation of ecotypes in herbal drug development. Indian J Pharmacol, 33, 2001,145.
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| Paper Type | : | Research Paper |
| Title | : | A Comparative study of the Antimicrobial activities of five varieties of essential oils from the seeds of Artocarpus |
| Country | : | India |
| Authors | : | Sirisha Nagala || Gangaraju Rapaka || Raghava Rao Tamanam |
Abstract: Hexane and methanolic oil extracts from five varieties of Artocarpus seeds were studied to explore its suitability for ethno medical uses. Crude hexane and methanolic oils were found to shown good to moderate activity against bacteria, in particular Gram +ve (Bacillus cereus, Bacillus subtilis and Staphylococcus aureus) and Gram-ve (Eschirichia coli and Pseudomonas aeruginosa) and fungal stains, more specifically Aspergillus niger, Aspergillus flavans, Candida albicans and Saccharomyces cerevisiae. Maximum activity was observed on bacterial strains compared with fungal strains.
[1]. Adebayo-TayoBC.,Ajibesin KK 2008. Antimicrobial activities of Coulaedulis. Res J Med Plant., 2:86-91.
[2]. Adebolu TT and Oladimeji SA 2005. Antimicrobial activity of leaf extracts of Ocimumgratissimum on selected diarrhea causing bacteria in Southwestern Nigeria. Afr J Biotechnol., 4: 682-684.
[3]. Anwar F., HussainAI.,Sherazi STH and Bhanger MI 2009. Changes in composition and antioxidant and antimicrobial activities of essential oil of fennel (Foeniculumvulgare Mill.) fruit at different stages of maturity. J Herbs Spices Med Plants., 15: 1-16.
[4]. Bayliss M 1936. Effect of the chemical constitution of soaps upon their germicidal properties. J Bacteriol., 31:489-504.
[5]. Bergsson G., Arnfinnsson J., Karlsson SM., et al 1998. In vitro inactivation of Chlamydia trachomatis by fatty acids and monoglycerides. Antimicrob Agents Chemother., 42:2290-2294.
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| Paper Type | : | Research Paper |
| Title | : | Biochemical Study on Endothelial Nitric Oxide Gene Polymorphism in Fatty Liver Patients |
| Country | : | Egypt |
| Authors | : | Rizk Ahmed El-Baz || Alaa Wafa || Nasser Mohammed Hosny || Sameh Refaat El-Saka |
Abstract: Endothelial nitric oxide synthase (eNOS) gene polymorphism association with non-alcoholic fatty liver disease (NAFLD). Objective: to check for association of polymorphism of eNOS gene with susceptibility and severity of NAFLD in cases from Egypt. Subjects: This work included 100 cases with NAFLD from Internal,liver unit and 100 healthy individuals. The mean age of cases was 45.45 ± 15.29 (range: 18 – 80 years).
[1]. Adams LA, Lymp J, St Sauver J, et al. (2005). The natural history of nonalcoholic fatty liver disease: a population based cohort study. Gastroenterology;129:113–21.
[2]. Alkharfy KM, Al-Daghri NM, Al-Attas OS, Alokail MS, Mohammed AK, Vinodson B, Clerici M, Kazmi U, Hussain T, Draz HM (2012): Variants of endothelial nitric oxide synthase gene are associated with components of metabolic syndrome in an Arab population.Endocr J; 59(3):253-63.
[3]. Angulo P. (2002).Nonalcoholic fatty liver disease. N Engl J Med; 346:1221–31.
[4]. Barshop N. J., Sirlin C. B., Schwimmer J. B., et al., ( 2008). Review article epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease," Alimentary Pharmacology and Therapeutics, vol. 28, no. 1, pp.13–24.
[5]. Begriche, K.; Igoudjil, A.; Pessayre, D.; Fromenty, B(2014). Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it. Mitochondrion, 6, 1–28. Int. J. Mol. Sci., 15 8734
[6]. Bjorkegren J., Beigneux A., Bergo M. O., Maher J. J., and Young S. G.,(2002). "Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury," Journal of Biological Chemistry, vol.277, no. 7, pp. 5476–5483.