Version-1 (March-April 2015)
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| Paper Type | : | Research Paper |
| Title | : | Comparative Study of Low Dose of Dexmeditomidine and Clonidine on the Characteristics of Intrathecal Bupivacaine - Prospective Randomized Study |
| Country | : | India |
| Authors | : | Dr A.Venkateswara Rao. || Dr S.Vinaya Kumar. || Dr K.Lakshmana Rao. |
Abstract: Introduction: Spinal Anaesthesia, most commonly used technique for lower abdominal surgeries as it is very economical and easy to administer. A number of adjuvants like midazolam, fentanyl, clonidine etc have been used to improve the quality of subarachnoid block. Dexmeditomidine an α2-adrenergic agonist which has α2/ α1 selectivity ratio eight times greater than Clonidine has been used recently as an adjuvant in various clinical trials. The aim of the study was to compare the Subarchnoid block characteristics with low dose dexmeditomidine or chlonidine added to intrathecal Bupivacaine.
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[3]. Alahuta S, Kangas-Saarela T, Hollmen AI, Edstrom HH. Visceral pain during caesarean section under spinal and epidural anaesthsia with bupivacaine. Acta Anaesthsiol Scand 1990;34:95-8.
[4]. Hunt CO, Naulty JS Bader AM, Hauch MA, Varikar JV, Datta S, et al. Perioperative analgesia with subarachnoid fentanyl-bupivacaine for Cesarean delivery. Anesthesiology 1989; 71:535-40.
[5]. Strebel S, Gurzeler J, Schneider M, Aeschabach A, Kindler C. Small-dose intrathecal clonidine and isobaric bupivacaine for orthopedic surgery: a dose response-study. Anesth Analg 2004; 99:1231-8.
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| Paper Type | : | Research Paper |
| Title | : | Status and Problems of Beekeeping in Mansa District of Punjab |
| Country | : | India |
| Authors | : | Dr. Jasvir Singh Dalio |
Abstract:Beekeeping as a village industry is of considerable importance but in study area it requires a lot of improvement in apicultural as well as in agricultural practices. Most of the beekeepers are facing problems due to lack of knowledge of bee management technology and related skills. This small cottage industry may be called in infancy in Mansa district of Punjab. Crop diversification, which can provide continuous succession of blooming bee forage, is urgently required .There must be a regional bee research and training centre to provide guidelines against threats to beekeeping like varroa mite and other serious bee diseases.
Keywords: Apis mellifera , Beekeeping , Bee behaviour , pollination , Queen rearing.
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| Paper Type | : | Research Paper |
| Title | : | Chemical Composition and Biological Activity of the Essential Oils Obtained From Yellow and Red Carrot Fruits Cultivated In Egypt |
| Country | : | Egypt |
| Authors | : | Noha Khalil || Mohamed Ashour || Abdel Nasser Singab || Osama Salama |
Abstract:The chemical composition of the essential oils from the fruits of Daucus carota var. sativus (yellow carrot) and var. boissieri (red carrot) was determined using GC/FID and GC/MS. Altogether; 29 and 32 compounds were identified accounting for 96.58 and 96.72 % of the total detected components in the hydrodistilled yellow and red carrot oils, respectively. Carotol constituted the major component in both oils (~66‒68 %). The antioxidant activity was assessed using both diphenylpicrylhydrazyl (DPPH•) and 2-deoxyribose degradation (2-DR) assays. Both oils reduced DPPH• and inhibit 2-DR with IC50 values of 12.71, 14.15, mg/ml and 87.15, 88.75 μg/ml for the yellow and red carrot oils, respectively. Inhibition of both 5-lipoxygenase (5-LOX) enzyme and prostaglandin E2 (PGE2) production were used to assess the anti-inflammatory activity. Yellow carrot oil showed better activity towards inhibition of 5-LOX (IC50 of 37.53 μg/ml). The cytotoxicity of both oils was determined against both MCF-7and HepG-2 cancer cell lines using the sulforhodamine B (SRB) assay. The highest cytotoxic activity was observed against HepG-2 cell with IC50 values ranging from 163-172 μg/ml for both oils. These results indicate promising antioxidant and anti-inflammatory activity of both oils and provide a rationale for their uses in many skin diseases.
Keywords: Antioxidant, Anti-inflammatory, Apiaceae, Cytotoxicity, Daucus carota, Essential oil.
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[6]. B.E. Van Wyk and M. Wink, Medicinal plants of the world : an illustrated scientific guide to important medicinal plants and their uses (Portland, Or.: Timber Press, 2004).
[7]. L. Boulos, Flora of Egypt (Cairo, Egypt: Al Hadara Pub., 1999).
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| Paper Type | : | Research Paper |
| Title | : | Identification of Targetable Virulence Factor and Drug Screening For Bacterial Pneumonia |
| Country | : | India |
| Authors | : | Ravikant Yadav || Nikita Chordia || Anil kumar || Shobha Shouche |
Abstract: Pneumonia is an infectious disease. This is prevalent in pandemic proportions across the Globe; especially in developing countries. It is one of the major causes of morbidity and mortality among infants and children. It is mainly caused by bacterial or viral infection. Irrespective of the abundant occurrence of bacterial pneumonia, there is no specific antibiotic therapy available. On the other hand non-specific therapies are less effective and may induce bacterial resistance. Therefore, in present work, we explored a common but novel target for four pathogenic pneumonia causing bacteria and also revealed the most specific antibiotic(s) to this target.We observed trigger factor protein as a common targetable virulence factor present in four pathogenic bacteria viz. Streptococcus pneumoniae, Klebsiella pneumoniae, Chlamydophila pneumoniae and Mycoplasma pneumoniae. After screening of 116 available antibacterial compounds, we found 04 most specific and potent antibacterial agents that inhibit the growth and survival of bacteria through trigger factor protein. The best efficacies showed by enoxacin, sulfamonomethoxine, carbadox and isoniazid.
Keywords: pneumonia, virulence, docking, screening, targetable, inhibitor.
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| Paper Type | : | Research Paper |
| Title | : | A Review on the Pollution and Phytoremediation of Romi Stream |
| Country | : | Nigeria |
| Authors | : | Ugya, A.Y || Umar, S.A |
Abstract: Romi stream receives effluent from Kaduna refinery which is believed to endanger the lives of the fauna and flora of the stream and even the inhabitants of Rido community, Researchers have make series of researches on the possible remediation of this pollution with phytoremediation being at the fore. This Review gives information on Pollution cases in Romi stream and bioremediation studies of Romi Stream.
Keywords: Effluent, Flora, Fauna, Rido Hausa, Heavy metals.
[1]. Akpor, O.B. andMuchie, M. (2010). Remediation of heavy metals in drinkingwater and wastewater treatment systems: Processes andapplications. Int. J. Phys. Sci. 5(12):1807-1817.
[2]. Al-Amin, M.A. (2013) Energy Production and Environmental Concerns in Nigeria: The Case of Kaduna Petroleum Refinery on its Host Community. Journal of Energy Technologies and Policy. 10(3) 69-77
[3]. Alkasim, A. BabaganaBukar, B. and Sule M. M. (2013)The effect of industrial effluent discharged by petrochemical refinery situated in Kaduna, Nigeria on the calorific value of some selected agricultural produce. Nigerian Journal of Physics (24)52-57
[4]. Asamudo, N.U., Daba, A.S. and Ezeronye, O.U. (2005). Bioremediation of Textile Effluent Using Phanerochaetechrysosporium., African Journal of Biotechnology. 4(13), 1548-1553.
[5]. Azizullah, A., Khattak, M.N., Richter, P. andHader DP (2011). Water pollution inPakistan and its impact on public health- A review. Environ. Int.37(02):479-97.
[6]. Chikogu, V., Adamu C. I. And Vivan E. L. (2012). Public Health Effect Of Effluent Discharge Of Kaduna Refinery Into River Romi. Greener Journal Of Medical Sciences. 2(3) 064-069.