iosr-JDMS   Volume-10 ~ Issue-1

Abstract: Stickler syndrome is a rare genetic connective tissue disorder ( incidence 1 in 7500 births) related to mutations in the collagen genes. One out of 4 patients with Stickler syndrome has a Pierre Robin sequence- detected at birth by a combination of retrognathia, micrognathia, cleft palate and retroglossoptosis. Ocular abnormalities, craniofacial anomalies, bone and joint symptoms and hearing loss are the main manifestations of Stickler syndrome. Early onset osteoarthritis with a prevalence of 15% before 20 years of age and 75% after 50 years of age presents with a variety of features including metaphyseal-epiphyseal dysplasia with broadening and stiffness of joints, pronated feet and moderate arachnodactyly – all of which were present in the 40 day old male infant that we are reporting. The unusual occurrence of arthropathy involving bilateral knee and shoulder joints with stiffness and broadening of affected joints detected so early in life, has not been reported so far to the best of our knowledge. This baby also presented with megalocornea and glaucoma together with other phenotypic abnormalities specific for Stickler syndrome. The early recognition of arthropathy and ophthalmopathy in the neonatal period in association with features of Pierre Robin sequence helped us to make the diagnosis of Stickler syndrome by 45 days of age. The idea of reporting this case is not only to make the pediatrician aware about the probability of diagnosis of Stickler syndrome in a newborn with Pierre Robin sequence as also to stress the need for regular follow up by an ophthalmologist and a test of hearing soon after birth and audiograms at diagnosis and at regular follow-ups. Regular monitoring from early infancy and through the teens for the above-mentioned problems with prompt interventions will go a long way in improving the quality of life in children with Stickler syndrome.

Keywords: Glaucoma ,Megalocornea, Osteoarthritis , Pierre Robin sequence , Stickler syndrome

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Abstract: Background and objective: Incisional hernia is one of the most common problems encountered by general surgeons worldwide. Many forms of repair have been adopted with their own merits and demerits. In thisretrospective study,an attempt is made to evaluate theoutcome of preperitoneal mesh repair of incisional hernia with reference to technicaldifficulty, convalescence, wound infection, bowel adhesions, intestinal obstruction, intestinal fistula formation and recurrence.

Keywords: preperitoneal, incisional hernia, complications, recurrence.

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Abstract: Introduction: Physical activity is defined as any bodily movement produced by skeletal muscles that requires energy expenditure. Physical inactivity has been identified as the fourth leading risk factor for global mortality causing an estimated 3.2 million deaths globally. Objectives: To find the physical activity status of the adolescent girls and to know their body image perception. Materials And Methods: The study was conducted at the Bagbazar Slum of Urban Field Practice Area of R.G.Kar Medical College. A total of 107 girls from 10 to 19 years of age residing in this slum participated in this study. A pre-designed, pre-tested questionnaire was used for data collection. For determining physical activity status Global Physical Activity Questionnaire (GPAQ) was used and the results were compared with the WHO guidelines for physical activity for adolescents. METs (Metabolic Equivalents) are used for the analysis of GPAQ data. MET is the ratio of a person's working metabolic rate relative to the resting metabolic rate. One MET is defined as the energy cost of sitting quietly and is equivalent to a caloric consumption of 1 kcal/kg/hour. Therefore, when calculating a person's overall energy expenditure using GPAQ data, 4 METs get assigned to the time spent in moderate activities, and 8 METs to the time spent in vigorous activities. Results: Only 14.28% of girls in the age group 10 to 17 years and 67.56% of girls above 17 years had physical activity above recommended guidelines. 57% of girls had no recreation involving physical activity of any kind. 47.7% of girls were not satisfied with their body image. Conclusion: Physical activity should be promoted among adolescent girls to prevent occurrence of NCD and lead a healthy life.

Key Words: Adolescent, Perception, Body Image, Physical Activity

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