Series-1 (Jul. – Aug. 2020)Jul. – Aug. 2020 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Effect of Ethyl Acetate Extract of Annona Muricata (Sour Sop) Leaf on Cyanide Induced Tissue Lesions in Rabbits of the Newzealand Strain |
| Country | : | Nigeria |
| Authors | : | Ukwuonwo Ada Chidimma || Ediale Osehahumen Michael || Okolie Ngozi Paulinus |
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: | 10.9790/264X-0604010112  |
Abstract: Chronic intoxication of cyanide is known to produce some pathologic effects on different tissues, leading to alterations in biochemical parameters. Natural products, especially those derived from plants, have been used to help mankind sustain its health since the dawn of medicine. One such plant with extensive traditional use is Annona muricata. This study was aimed at determining the effects of ethyl acetate extract of Annona muricata leaves on cyanide (CN) induced tissue lesions in rabbits of the New Zealand strain. Four groups of rabbits,(5 per group) were used for the study. Group A(positive control), received pure grower's mash. Group B(negative control) receivedgrower's mash which had been compounded with 400mg CN/kg of feed. Group Creceived grower's mash.....
Key Words: Annona muricata, Ethyl acetate, Cyanide.
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[2]. Mathangi, D. C., Namasivayam, A. (2000). Effect of chronic cyanide intoxication on memory in albino rats. Food Chemistry and Toxicology .38:51–55.
[3]. Okolie, N. P., Iroanya, C. U. (2003). Some histologic and biochemical evidence for mitigation of cyanide-induced tissue lesions by antioxidant vitamin administration in rabbits. Food Chemistry and Toxicology.41:463–469.
[4]. Okolie, N. P., Asonye, C. C. (2004). Mitigation of cataractogenic potential of cyanide by antioxidant vitamin administration. Journal of Medicine and Biomedical Research.3:48–52.
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| Paper Type | : | Research Paper |
| Title | : | Relationship between MTHFR Gene Polymorphism [C677T] and Risk of Breast Cancer |
| Country | : | Egypt |
| Authors | : | Thoria Ahmed Omar || Waleed Mohamed Fathy || Mohamed Sabry Ammar || Alshimaa Mahmoud Alhanafy || Doha said sayed |
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: | 10.9790/264X-0604011318 |
Abstract: Background: Breast cancer is a complex disease, constitutes a main community health concern. Mutation in tumor suppressors' genes and oncogenes were involved in its pathogenesis. Methylenetetrahydrofolate reductase helps in the 5, 10-methylenetetrahydrofolate transformation into 5-methyltetrahydrofolate. 5-methyltetrahydrofolate assists in the re-methylation of homocysteine to de novo methionine necessary for DNA production. In this study we analyze the relationship between the MTHFR gene C677T [rs1801133] polymorphism and the risk of breast cancer. Materials and Methods: This case–control study was carried out on 50 women with breast cancer and 50 women who apparently healthy. Real time polymerase chain reaction technique was used to detect MTHFR gene C677T [rs1801133] polymorphism.....
Key Words: Breast cancer, gene polymorphism, Methylenetetrahydrofolate reductase, real-time polymerase chain reaction.
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[5]. Elizabeth KE, Praveen SL, Preethi NR, et al. (2017): Folate, vitamin B12, homocysteine and polymorphisms in folate metabolizing genes in children with congenital heart disease and their mothers. European Journal of Clinical Nutrition; 71[12]: 1437.
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| Paper Type | : | Research Paper |
| Title | : | A Review on Genetically Modified Organisms and Foods- Perspective and Challenges |
| Country | : | India |
| Authors | : | Sanjay Mishra || Ram B. Singh || Prashant Saxena || Amit Kumar Mani Tiwari || Abbas Ali Mahdi |
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: | 10.9790/264X-0604011925 |
Abstract: The ratio of the human population and the quantity of the eatable items are inversely proportional. The quantity of food items is decreased due to certain reasons such as, environmental conditions, unavailability of the water for farming, less income of farmers etc. The principal problem, concerning with GMO (Genetically Modified Organism) is the less information available in the public domain. Still the method for development of organism is bizarre for the public. Considering it, this compilation is aimed to sketch out the pitfalls for the implementation of GMO in the real world, and the advantages of GMO for the betterments of human society are listed. This overview will provide the detail information about the listed problems and shed off the myths and also open up the new paths to bring out the solution for the available problem in the area of genetically modified organism .
Key Words: GMO, GMO crops, Patenting of GMO, Pitfall of GMO.
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